Susan Hasty, Publisher
Table of Contents . . . July 4th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Pharma Investments, Ventures and Law Weekly | Other Publications
ARYx Therapeutics Inc. - Pharmaceutical R&D company completes $55M Series D financing
ARYx Therapeutics, Inc. - Drug discovery firm completes series D financing
Advanced Neuromodulation Systems - Pain therapy device firm announces stock repurchase plan
Alexion Pharmaceuticals, Inc. - Pharmaceutical company reports loss of $0.69 per share
American Oriental Bioengineering - Chinese biotech firm issues update on AMEX listing
Array BioPharma, Inc. - Milestone payment issued from Amgen as part of drug R&D deal
BioTrove, Inc. - Alan Barber named chief financial officer at biotech firm
Calypte Biomedical Corporation - HIV diagnostic test maker raises $9.3M in private placement
CeMines, Inc. - David Busam named VP of finance/administration, CFO at genomics firm
Eon Labs, Inc. - Increase in number of authorized shares of stock approved at pharmaceutical firm
Epix Medical, Inc. - MRI pharmaceuticals company prices $75M offering
Eyetech Pharmaceuticals, Inc. - Eye-disease focused company completes secondary public offering
Finance - $4.6M private placement completed for obesity disease management firm
Finance - HealthExtras' executives adopt 10b5-1 plan
Genitope Corp. - Cancer immunotherapies company announces closing of public offering
Aarhus University - Hormonal variation may influence risk
Academia Sinica - Hapten receptors bear selective delivery of imaging and therapeutic agents
Acquired and Inherited Diseases - Targeted Genetics signs exclusive license agreement with NIH
Aerogen, Inc. - Distribution deal signed for Aeroneb Professional Nebulizer System
Ajou University - Priming deficient polymerase in HBV core particle allows for oligomer synthesis
Albany College of Pharmacy - Low-molecular-weight heparins may interfere with tumor growth and metastasis
Allos Therapeutics, Inc. - Application filed for European marketing approval of RSR13 (efaproxiral)
Alpharma, Inc. - Pharmaceutical firm announces changes to its board of directors
American Orthopaedic Foot & Ankle Society - Shockwave therapy offers non-invasive treatment for heel pain
American Pharmaceutical Partners - Nanoparticle form of paclitaxel is active in patients who failed taxane therapy
Antigen Express - Generex prepares for trials in patients with Her-2/neu positive ovarian cancer
Applied DNA Sciences, Inc. - DNA-embedded security solutions provider announces new president
Asthma Epidemiology - Declining asthma rates in Mexico may indicate end of epidemic
Benaroya Research Institute - IRS1 variant linked to type 1 diabetes in families from U.S. and U.K.
Bio-Rad Laboratories, Inc. - Agreement in principle signed to acquire MJ Research
Biotech Holdings - Sucanon marketing agreement signed for Mexico
Boston Scientific Corporation - Advanced Bionics acquired for $740M in cash
Burnham Institute - EphB4 and ephrin-B2 interactions modulate breast tumor growth
CBR Institute for Biomedical Research, Boston - CXCL12 mediates CCR7-independent homing of central memory cells
CHU Cote Nacre, Caen - Virologic failure in HIV patients associated with poor adherence to NNRTIs
CHUL Research Center, Quebec City - BM stem cells populate CNS into fully differentiated parenchymal microglia
CJW Vascular Medical Center - Combination therapy to treat acute blocked peripheral arteries evaluated
CSIC - SIKVAV retro and retro-enantio analogues take aim at metastatic events
Cancer Death Rates - Study finds rising death rates from prostate cancer after 15 years
Cancer Risk - Illinois holding international conference on PCBs
Cancer Treatment - Gene activity may change as breast cancer progresses
Cancer Treatment - Genetic differences explain severity of chemotherapy side effects
Cancer Treatment - Study shows virus can indicate cancer's aggressiveness
Cardiac Science, Inc. - AED distribution pact signed for People's Republic of China
Cardinal Health, Inc. - Device firm commences offer to acquire Alaris Medical Systems
Cedars Sinai Medical Center, Los Angeles - Microdissection-based genotyping aids reactive gliosis vs. glioma diagnosis
Celsion Corp. - Biotech firm submits response to FDA warning letter
Centers for Disease Control & Prevention - Guide to sexually transmitted disease resources on Internet released
Centers for Disease Control & Prevention - Measles outbreak epidemiology in the U.S. in 1993-2001 reported
Centers for Disease Control & Prevention - Vaccination levels associated with lack of measles in preschoolers
Centers for Disease Control & Prevention - Vaccine-induced antibodies to measles persist 26 to 33 years
Central South University - PLL-modified silica nanoparticles transport antisense oligonucleotides
Centro de Investigacion y Estudios Avanzados - Salmonella epitopes for CD8+-T-cell recognition identified
Chiba University - Renal cancer tumor vessels express a member of the RGS superfamily
Children's Hospital Oakland Research Institute - New Neisseria meningitidis candidate vaccine identified
Chinese University of Hong Kong - Study assesses treatment-seeking behavior of Chinese women in Hong Kong
ChromaVision Medical Systems, Inc. - Medical device firm names Allred as consulting pathologist, board member
Cleveland Clinic Foundation - Rasburicase mitigates the nephropathic effects of tumor lysis syndrome
Cochin Hospital, Paris - Immunohistochemistry provides reliable determination of HER-2/neu status
Coremed, Inc. - Oral insulin developer retains financial advisory firm
Curon Medical, Inc. - Secca clinical patient registry for bowel incontinence treatment
DNAVec Research Inc. - Post-ischemic neurotrophic factor gene transfer prevents delayed neuronal death
Dana Farber Cancer Institute, Boston - HIV-1 virions induce apoptosis through a CXCR4- or CCR5-dependent pathway
Dubrava University Hospital - Immunosuppressive therapy can rapidly resolve acquired postpartum hemophilia
Duke University - Elderly, diabetics, women at risk for postsurgery infection
Emergency Filtration Products, Inc. - FDA certificate to export products to Japan granted for RespAide
Exelixis, Inc. - Phase I trial for anticancer compound Xl647 initiated
Federated University of Para - Hydroxyurea may cause acute leukemia in patients with sickle cell disease
Fitness & Obesity - Pediatricians urged to advise patients on obesity
Fox Chase Cancer Center, Philadelphia - Hepatitis delta virus antigenomic RNA transcripts undergo alternate processing
Frost & Sullivan - Biological response modifiers' image dominates arthritis therapies despite price
Fukui Medical University - Tumor grade correlates with fluorodeoxyglucose uptake in ovarian cancer
Genentech, Inc. - Avastin study shows extended survival in metastatic colorectal cancer patients
Genetronics Biomedical Corp. - Results on electroporation-enhanced DNA vaccine delivery presented at meeting
Georges Pompidou European Hospital - 4-ASA enemas well-tolerated by patients with 5-ASA-induced pancreatitis
GlaxoSmithKline Pharmaceuticals - Functional nuclear MRI is applied to in vivo anticancer research
Graz University - Stenting can enhance treatment for cervical artery dissection
HIV/AIDS Prevention - Experts say AIDS prevention and treatment should be integrated to fight epidemic
Hacettepe University, Ankara - Celecoxib is a potent chemopreventive agent
Hamamatsu University - Glycine cleavage system abundantly expressed in embryonic neural stem cells
Harvard University - Pantothenate auxotroph of M. tuberculosis protects guinea pigs
Harvard University - Pin1 may link signal transduction to cancer and Alzheimer disease
Health Canada - Unique variant of disease-causing meningococci characterized
Health Protection Agency, London - Pneumococcal vaccine not cost-effective for all elderly adults
Hopital Saint-Eloi - Clubfoot with survival of motor neuron 1, telomeric gene deletion reported
Hormone Replacement Therapy - Long-term tibolone therapy appears to benefit lipid profile
Hubei Pharmaceutical Group - Company to acquire controlling interest in HBBenda
Hunan Normal University - HindIII marker of osteocalcin gene limited as genetic marker in Chinese women
INSERM U563, Toulouse - Dihydropyridine receptors are selective markers of Th2 cells
IQ Corp. - Dutch biopharma enters collaborative agreement with NMRC
Immucor, Inc. - Transfusion company announces 3-for-2 stock split and stock repurchase program
Immunetics, Inc. - CDC collaboration yields new test for anthrax
InSightec, Ltd. - FDA panel recommends ExAblate System for approval
Institute of Hematology, Tianjin - Fetal BM-derived Flk1+ CD34- stem cells are ideal as treatment source
Intl. Hepato-Pancreato-Biliary Association - Liver cancer expert presents new data on SIR-Spheres
Introgen Therapeutics, Inc. - Clinical safety, efficacy data of Advexin featured at scientific meeting
Janssen Pharmaceutica Products, L.P. - Risperdal reduces acute bipolar mania symptoms as early as day 3 of treatment
Johns Hopkins Medical Institute - Laparoscopic lymph node dissection is feasible for some testicular cancers
Johns Hopkins University - XIAP is key modulator of TRAIL-mediated apoptosis in tumor cells
Karolinska Institute - Referral to district hospitals key to improving care for severely ill children
Karolinska Institutet - Opsonic antibodies target fibrinogen binding protein of Staphylococcus
Kyoto University - Alpha-actinin recruits SPA-1 to immunological synapse
Kyoto University - The 5-fluorouracil derivative UFT foils non-small cell lung cancer angiogenesis
Linkoping University - Third heart sound can occur in patients with heart failure
Lipid Sciences, Inc. - Company focused on lipids announces sale of real estate assets totaling $5.4M
Louisiana State University - The inflammatory response may be important in cardiovascular disease
Maisonneuve-Rosemont Hospital - Bleomycin resistance stems from faulty transport mechanisms
Max Delbruck Center, Berlin - c-FLIP mediates resistance of HRS cells to death receptor-induced apoptosis
Max-Planck-Institute for Experimental Medicine - Link suspected between soccer and amyotrophic lateral sclerosis
McGill University - Fixed-trypomastigote EIA may be a suitable candidate for blood bank screening
Medco Health Solutions, Inc. - Brand medications preferred over generics for serious conditions, survey shows
Medical College of Wisconsin - To defeat bioterrorism, more international collaboration is needed
Medrad, Inc. - Consorta inks supply agreement for vascular injection system, related products
Millennium Pharmaceuticals, Inc. - Company acquires rights to novel proteasome inhibitors and related technology
Mirus Bio Corp. - Company announces new intravenous gene-delivery method
Monash University - Leptin released within brain at increased rate in obese humans
Nastech Pharmaceutical Co., Inc. - PAI complete for nasal-spray facility
Natl. Jewish Medicine & Research Center, Denver - Cytosolic phospholipase A2 alpha targets the phagosome membrane
Ohio State University - Folate receptors ensure correct delivery of tumor-selective gene therapy
Oregon Health & Science University - Estrogen boosts memory in men with prostate cancer
Orthovita, Inc. - Synthetic biomaterial restores function after vertebral compression fractures
Osaka University - Streptozotocin injections cause early onset of glomerulosclerosis
Oxford University - Selenium in fingernails is not linked to prostate cancer risk in British men
Panacos Pharmaceuticals Inc. - Merger produces pipeline of products for serious infectious diseases
Panacos Pharmaceuticals, Inc. - Single-dose phase I trial of first-in-class HIV maturation inhibitor completed
Par Pharmaceutical Companies, Inc. - Development and marketing agreement signed for novel formulation of amoxicillin
Paxis Pharmaceuticals, Inc. - Integrated BioPharma delivers update on paclitaxel API
Pharmaceutical Drugs - FDA accuses maker of antiretroviral of misleading promotions
Pharmessen Scientific, Inc. - Nutraceutical/pharmaceutical company selects Central American distributor
Pharsight Corporation - Software/strategic services provider announces senior VP, business development
Phase III Medical, Inc. - NeoStem granted license to operate adult peripheral blood stem cell bank
Phylonix Pharmaceuticals, Inc. - NIH awards phase II SBIR to develop zebrafish apoptosis drug-screening assays
Prince of Wales Hospital, Hong Kong - Psychiatric morbidity, marital maladjustment affect Chinese menopausal women
Priority Healthcare Corporation - Specialty distributor provider chosen for Apokyn Parkinson therapy
ProMetic Biosciences, Inc. - Hemosol completes agreements to license Cascade technology
Quidel Corporation - Diagnostic tests provider announces new board chairman
Rafael Medical Technologies, Inc. - SafeFlo Retrievable Vena Cava Filter receives CE Mark approval
Russian Academy of Medical Sciences - T-cell dysfunction characterized in chemotherapy-treated lymphoma patients
Russian Academy of Sciences - Novel assay provides rapid detection of 2,4-D and simazine pesticides
SGX - Drug discovery company announces completion of two validation milestones
Santa Croce Hospital - Percutaneous intra-arterial catheter implantations transport liver cancer drugs
Semmelweis University of Medicine - Hsp90 inhibitors enhance complement-induced tumor cell lysis
Seoul National University - Capsaicin changes neuropeptide Y and cholecystokinin expression
SeraCare Life Sciences, Inc. - Genomics Collaborative acquired through stock deal
Slotervaart Hospital, Amsterdam - Atazanavir and tipranavir quantified in plasma by HPLC plus MS/MS
Southern Illinois University - Failed scalp replantation can induce dangerous psychological sequelae
Spinal Concepts, Inc. - Nex-Link Implant system launched for posterior cervicothoracic spinal fixation
St. Jude Children's Research Hospital - New laboratory model can be used to test new treatments for pediatric eye cancer
State University of Ghent Hospital - Cancer drugs and irradiation combine to overcome liver cancer proliferation
Stratagene Corp. - Diagnostics company satisfies NASDAQ's initial listing requirements
SurModics, Inc. - New polymer technologies introduced for site-specific drug delivery
Symphogen A/S - Biotechnology company announces appointment of new board member
Taipei Medical University - Four pH-dependent formation constants for free PSA elucidated
Takeda Pharmaceuticals North America - Trial tests diabetes drug in treatment of multiple sclerosis
Tel Aviv University - B. anthracis antigens for testing anthrax immunity identified
Templeton Imaging Medical Corp., Inc. - Molecular Imaging signs imaging services agreement
Thermogenesis Corp. - U.S. Patent Office requested to re-examine cord blood stem cell patent
U.S. National Cancer Institute - Recombinant anti-MUC1 scFv has improved stability
U.S. National Institutes of Health - Proteasome inhibition boosts viral replication in an HBX-dependent manner
Univ. of California, Los Angeles - Antimicrobial drug development declining
Univ. of California, San Diego - Tension-free vaginal tape reduces maximum flow rates
Univ. of California, San Diego - UCSD partners with Peru in NIH grant to battle world's number 2 killer
Univ. of Miami School of Medicine - Prepartum, postpartum, and chronic depression effects on newborns studied
Univ. of Texas Health Science Center, San Antonio - Incidence of methicillin-resistant S. aureus infection high in prison population
Univ. of Texas, Houston - Abolished interaction of NUB1 with AIPL1 linked to Leber congenital amaurosis
University of California, Davis - Patients in Japan, U.S. react differently to the same chemotherapy regimen
University College London - Fat cells could provide the key to a longer life
University North, Cape Town - Misconceptions regarding condom use have implications for HIV prevention
University of Alabama - CCK-8 response changes after MC3/4-receptor blockade reported
University of Amsterdam - WNT signals encourage multiple myeloma cell proliferation
University of Antwerp - Bead-based assay is a poor model of apoptotic cell phagocytosis
University of Bristol - Knee surgery in the U.K. has soared over 300% in a decade
University of Buenos Aires - Multicellular tumor spheroids model HSVtk/ganciclovir systems in vitro
University of Calgary - Active contour models help identify breast boundary in mammograms
University of California, Davis - When combining new oral agents with standard chemotherapy, timing may be crucial
University of Firenze - Influence of HLA-DRB1 alleles on MS risk elucidated
University of Florida - Researchers detect blood vessel dysfunction linked to heart disease in children with diabetes
University of Glasgow - Mutant of response-regulator homologue from Streptococcus crystallized
University of Graz - Lymphocyte dopamine receptor expression linked to persistent personality
University of Heidelberg - Major 5' site mutation renders CMV-driven HIV-1 proviral clone Tat-dependent
University of Kiel - Maternal IgG appears phenotypically in offspring as non-genetic inheritance
University of Leipzig - Aminoglycoside rescues disease-causing mutation in vasopressin receptor gene
University of Malaga - Puupehenone and associated compounds are angiogenesis inhibitors
University of Manitoba - Total IgE measurement is valid surrogate for antigen-specific IgE
University of Montreal - Role of anchoring proteins in cardiac sudden death investigated
University of Paris 05 - Dendrites cross-present HIV antigens from live and apoptotic infected CD4+ cells
University of Pennsylvania - Early NO inhibition augments HSV-1 intranasal infection
University of Pennsylvania - Olfactory dysfunction occurs in mice overexpressing human tau protein
University of Porto - Downregulated Bcl-2 or xIAP enhances the efficacy of breast cancer chemotherapy
University of Rochester - Many cancer patients turn to complementary therapies for healing
University of Roma Tor Vergata - Vertebroplasty and kyphoplasty ameliorate cancer-derived fracture pain
University of Roma Tor Vergata, Rome - Evidence of increased apoptosis/reduced proliferation in tazarotene-treated BCC
University of Rome "Tre" - Albumin-containing sol-gel glasses developed
University of S. Florida - Ipsilateral-mammogram computer-aided detection helps reduce false positives
University of Tokyo - Prognostic marker candidates for neuroblastoma identified
University of Turku - KA-induced neuronal death in immature OHCs region-specific and irreversible
University of Utah - Cryptic 6q subtelomeric deletion characterized
University of Wales - Intestinal bypass syndrome presents as erythema nodosum
University of Washington - Certain symptom patterns may provide clues for presence of ovarian masses
University of Wisconsin - StcE may protect E. coli O157:H7 and host cell from complement-mediated lysis
V.N. Karazin Kharkiv National University - Nonstoichiometric hydroxyapatite granules effective in orthopedic surgery
VasGene Therapeutics, Inc. - Researchers show potential of fighting angiogenesis
Vectron Therapeutics AG - Endothelial cell-specific human antibodies might retard tumor growth
Washington University - Human subjects play mind games
Wilhelminenspital, Vienna - FDG-PET not suitable for lymph node metastasis testing
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