Susan Hasty, Publisher
Table of Contents . . . July 11th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Pharma Investments, Ventures and Law Weekly | Other Publications
Alliance Pharmaceutical Corp. - Pharmaceutical company receives commitments for $11M financing
Alnylam Pharmaceuticals, Inc. - Biopharmaceutical firm exercises underwriters' over-allotment option
BioNumerik Pharmaceuticals, Inc. - Pharmaceutical company files for initial public offering
Biovail Corporation - Pharmaceutical company amends 2004 stock option plan proposal
CV Therapeutics, Inc. - Biopharmaceutical company sells $25M in convertible notes
Depomed, Inc. - Pharmaceutical company acquires remaining interest in subsidiary
Encysive Pharmaceuticals - Pharmaceutical company files $150M universal shelf registration statement
Finance - Affymetrix boosts earnings estimate
Finance - Rite Aid reports a 4.8% increase in same store sales for May
Kos Pharmaceuticals, Inc. - Kos obtains settlement for trademark infringement of Advicor
Labcyte, Inc. - Patents issued for acoustics to manipulate liquids
Lumenis, Ltd. - Laser maker reports preliminary first quarter revenue of $65.1 million
Memory Pharmaceuticals Corp. - Jzaneen A. Lalani named VP legal affairs
Protein Design Labs, Inc. - Therapeutics company announces executive appointments
Repligen Corporation - Biopharmaceutical company reports fourth quarter financial results
Abbott Laboratories - FDA accuses maker of antiretroviral of misleading promotions
Abgenix - Data: Panitumumab has single-agent antitumor activity in colorectal cancer
Academy Ziekenhuis Maastricht - Elective single embryo transfer percentage reflects quality of institution
Advanced Neuromodulation Systems - Neuromodulation company comments on acquisition of Advanced Bionics
Agennix Inc. - Results from phase I/II cancer trials with rhLF presented at ASCO
Allos Therapeutics, Inc. - Data from phase III trial of radiation sensitizer presented at ASCO
Alltracel Pharmaceuticals Plc - Biotech company announces entry into European surgical devices market
Altea Therapeutics - Insulin patch maker expands its capabilities with new directors
American Academy of Allergy, Asthma & Immunology - Prevalence, exposure to mouse allergen may contribute to asthma
American Diabetes Association - Report: Islet cell transplant program for type 1 diabetes successful
American Society of Clinical Oncology - NSABP protocol C-06: Oral chemotherapy equally effective and tolerated
American Society of Neuroradiology - Advancements in imaging enhance diagnosis, treatment of neurological diseases
Antoine Beclere Hospital - Severe infections plague acute alcoholic hepatitis patients given infliximab
Aphton - Regulatory submission of pancreatic cancer therapy begins in Switzerland
Aspect Medical Systems, Inc. - Device maker announces sale of common stock to Boston Scientific
Avanir Pharmaceuticals - Anthrax antibody profiled in medical journal
BBK Healthcare, Inc. - European survey identifies need for more education surrounding clinical trials
Bayer - Diabetic men are at greater risk for developing erectile dysfunction
Baylor College of Medicine - Researchers compare two methods of diagnosing congestive heart failure
Biomol International - Study: Red wine dietary supplement may activate Sirtuin 1 gene
Biophan Technologies, Inc. - Worldwide rights acquired for MRI-safe ceramic motor
Brigham & Women's Hospital - TAMs accumulate at similar rates during ZDV or d4T treatment
California Dept. of Health Services - Fast-food beef tacos blamed for multistate E. coli outbreak
Cancer Research U.K. - Hematopoietic growth factors manage the effects of non-Hodgkin lymphoma therapy
Cancer Treatment - University of Connecticut planning to make cancer center one of nation's elite
CancerVax Corporation - Data released on Canvaxin in treatment of patients with Stage IV melanoma
Caprion Pharmaceuticals - Therapeutic antibody program acquired from Sunol Molecular
CardioTech International, Inc. - DermaPhylyx awarded "Medicare Participating Provider" status
Catholic University of the Sacred Heart, Rome - Priming with rhG-CSF enhances gemtuzumab-ozogamicin efficacy in AML
Cecil Clinic, Lausanne - Sirolimus-eluting coronary stents effective in routine clinical practice
Cel-Sci Corp. - Phase II trial results for Multikine treatment released at ASCO
Cell Genesys, Inc. - Final results of phase I/II trial of CG7870 reported
Center for Environmental Hlth, Dallas - Toxic exposure to molds and mycotoxins yield abnormal neurological functions
Centers for Disease Control & Prevention - Lessons from measles surveillance in the U.S. outlined
Centers for Disease Control & Prevention - Overall population immunity to measles in U.S. is 93%
Centro Inves Estudios Avanzados IPN, Mexico City - La protein binds to NS5 and NS3 and to 5' and 3' ends of Dengue 4 virus RNA
Chelsea & Westminster Hospital, London - HIV-related germ cell tumor not more aggressive than GCT in general population
Chembio Diagnostic Systems, Inc. - Tuberculin-boosted antibodies correlate with immunity in cattle
Complementary and Alternative Medicine - MayoClinic.com adds dietary supplements search tool
Copernicus Therapeutics, Inc. - Progress reported in development of non-viral gene transfer aerosol product
Curtin Univ. of Technology, Perth - New HIV-1 integrase inhibitors developed
Cytokinetics, Inc. - Phase I results for SB-715992 presented at ASCO
Duke University - Researchers introduce noninvasive cineangiography by MRI
Emory University - Hypoxia-inducible factor 1 alpha is expressed early in prostate malignancies
Emory University Hospital - Atrophy sets adenocarcinoma apart from pancreatic intraepithelial neoplasia
European League Against Rheumatism - Deficiencies in healthcare provision exposed
Federal University of Sao Carlos - Alternagin-C is an angiogenesis activator
Fischer Imaging Corporation - Three SenoScan systems to be installed at California-based breast center
Fred Hutchinson Cancer Research Center - Counseling improves women's functioning
Free University of Berlin - Rubral GABAergic inhibition has little effect on paroxysmal dystonia
Free University of Brussels - pH-sensitive toxins find application in vaccines and drug delivery
GTx, Inc. - Positive ACAPODENE data presented at ASCO meeting
Genentech, Inc. - Avastin, Tarceva combination yields initial promising results for cancers
Genentech, Inc. - Rituxan plus chemotherapy improves survival in aggressive NHL study patients
GenoMed, Inc. - West Nile encephalitis patients respond promptly to new treatment
Georgia Institute of Technology - The efficacy of electroporation is divergent in multicellular environments
Geospiza - Companies to offer DNA sequencing instruments, analysis software as a package
GlaxoSmithKline - Positive results released from two Bexxar studies
Global HIV Prevention Working Group - Experts: Integrate AIDS prevention and treatment to fight epidemic
Gynecologic Surgery - End-to-end cervico-cervical anastomosis is feasible if necessary
Harris Interactive - Survey: Most think drugs should be prescribed for FDA-approved uses only
Harvard University - Anal Pap smears inaccurate predictor of high-grade anal dysplasia
Harvard University - Cell surface receptor SLAM controls T-cell and macrophage activity
Harvard University - Methyltestosterone may help fight CHD in surgically postmenopausal women
Hokkaido University - Novel murine model of Hantaan virus infection developed
Hospital 12 de Octubre - Irbesartan benefits diabetic patients at any stage of renal disease
IVAX Corp. - FDA grants approval of generic Ciprofloxacin tablets
ImaRx, Inc. - Ultrasound could be used to get drugs to tumors
Indiana University - Maintenance therapy discontinuation for histoplasmosis safe after HAART response
Inex Pharmaceuticals Corporation - Epicutaneous CpG oligodeoxynucleotides with antigen promotes CTL
Institut Pasteur de Tunis - Leishmania amastigotes induce transcription factor in macrophages
Institute Clinical & Experimental Med - Intra-abdominal fat during controlled weight reduction quantified
Institute of Human Virology - New strategies detect HIV earlier and more effectively than ever
Johns Hopkins University - Glucose sensors incorporating closed loop insulin delivery reviewed
Johns Hopkins University - Improved nutrition could prevent more than half of the world's child deaths
Juntendo University - Fyn kinase gene polymorphisms not linked to sporadic Alzheimer disease
Kagawa Nutrition University - Phycocyanin plus antigen-entrapped microparticles enhance IgA response
Keryx Biopharmaceuticals, Inc. - Company initiates phase II corporate clinical program for KRX-0401 (Perifosine)
Kos Pharmaceuticals, Inc. - New patent covers biopharmaceutical characteristics of Niaspan and Advicor
Kyoto University - Sphingomyelin synthase 1 plays a critical role in the growth of lymphoid cells
Kyungpook National University Hospital - Early absolute lymphocyte count useful prognostic marker for infection after SCT
Kyushu University of Hospital - Pemirolast is a potent reliever of paclitaxel-induced allergic reactions
M.D. Anderson Cancer Center - Manipulating master molecule disrupts vascular environment for tumors
Mardis, Aibel and Associates, LLC - Study: Common management practices can cost typical biotech company $2B
Mayo Clinic & Mayo Foundation - Rad9 protects cells from topoisomerase-mediated death
Mazor Surgical Technologies - U.S. FDA approves miniature robot for spinal procedures
McGaw Medical Center, Chicago - OC educational program for black women shows short-term success
McGill University - New target to control asthma identified
Mental Health - Communities around Pennsylvania start teen mental health screening
Merck KGaA - Trials show Erbitux provides new options for patients with colorectal cancer
Milestone Scientific, Inc. - CompuMed maker announces appointment of new auditors and election of new CFO
Moll Industries, Inc. - Medrad and plastics company extend partnership
Mount Sinai Hospital, Chicago - Increased HIV testing in underutilized venues may increase HIV status awareness
NASA Ames Research Center - Lower body negative pressure suitable for simulating gravity effects
National Public Health Institute, Finland - Environmental and dietary causes of type 1 diabetes reviewed
National Research Council Canada - Multiring radio-frequency coils suitable for MR microimaging
National Taiwan Univ. Hospital, Taipei - HBV/HIV coinfected patients increased risk for virologic failure after HAART
Netherlands Cancer Institute - BRCA1 germline carriers are at risk for more than ovarian cancer
Netherlands Cancer Institute - Oncogenic marker is a powerful prognostic tool
New York State Department of Health - Huntington disease transgenic mice exhibit early behavior abnormalities
Niigata University - Bio-Oss promotes bone formation in rats
Nuclear Policy Research Institute - Study documents dramatic increase in thyroid cancer in women and children
Nutrition 21, Inc. - Chromium supplementation may improve glucose and insulin metabolism
OSI Pharmaceuticals, Inc. - Company summarizes survival benefits in key patient subsets from BR.21 study
Ohio State University - Abnormal chromosomes forecast leukemia relapse
Osaka Bioscience Institute - ADP-ribosylation factor 6 is an integral component of breast cancer invasion
Peninsula Pharmaceuticals, Inc. - Patient enrollment begins in Doripenem trial for hospital-acquired pneumonia
Pennsylvania State University - Control of alternative sigma factor in E. coli described
Pintex Pharmaceuticals, Inc. - Pin1 enzyme may lead to development of more precise cancer treatments
Poliomyelitis - Health officials say Botswana polio campaign was wake-up call to the world
Quintiles Transnational Corp. - Drug development services provider receives CDISC certification
R2 Technology, Inc. - CAD developer names interim president and chief executive officer
RIKEN - Retinoic acid receptor-alpha-selective agonist prevents allograft rejection
Ranbaxy Pharmaceuticals Inc. - Panixine Disperdose launched for treatment of skin infections
Recom Managed Systems, Inc. - Life sciences company announces new member of medical advisory board
RegeneRx Biopharmaceuticals, Inc. - Biopharmaceutical company adds medical and scientific advisory board member
Regina Elena National Cancer Institute, Rome - Carboplatin and weekly paclitaxel safely manage advanced lung cancer
Roche Pharmaceuticals - Long-term relief from arthritis could evolve from B-cell targeted treatments
Royal Melbourne Hospital - Re-entrant tachycardia reported in patient with normal ventricular function
STAAR Surgical Company - Ophthalmic product manufacturer to sell 2.0 million shares of common stock
Saint Antoine Hospital - GemOx more effective than gemcitabine alone in pancreatic cancer study
Science Institute Casa Sollievo Sofferenza - Female AI patients with hypercortisolism are at risk for low spinal BMD
St. Bartholomew's Hospital - Early therapy start improves exacerbation outcome in COPD
St. George Hospital, Syndey - Questionnaire proves valuable as an outcome measure in USI patients
Stanford University - Research shows hormonal regulation of the immune response
State University of New York - Treatment of insulin resistance in diabetes reviewed
Stony Brook University - MPI classification stability is questionable
Substance Abuse - Sober.com releases Sobersystems to reduce substance abuse relapse
Sunnybrook & Women's College, Toronto - Versican isoform induces neuronal differentiation and promotes neurite outgrowth
Synovis Life Technologies, Inc. - Medical device company expresses sympathy on death of board member
Synteract, Inc. - Successful upgrade of ORACLE Adverse Event Reporting System announced
Taipei Veterans General Hospital - 3D technology pinpoints origins of irregular heart beats
Tapestry Pharmaceuticals, Inc. - Tapestry data highlights potential of NBT-287 in paclitaxel-resistant tumors
Technical University of Munich - Ascorbic acid makes cancer cells insensitive to chemotherapy
Teva Pharmaceutical Industries Ltd. - Pharmaceutical company receives FDA approval of ciprofloxacin tablets
The Immune Response Corporation - New data on Remune suggests HIV-1 specific immune responses
Therion Biologics Corporation - Vaccine shows promise in advanced pancreatic cancer, data shows
Three Rivers Pharmaceuticals, LLC - Generic drug manufacturing company announces dismissal of ICN appeal
Tufts University - Stromal tissue is the key target of mammary gland carcinogens
U.S. Centers for Disease Control and Prevention - Ad campaigns against drunk driving may be effective
U.S. Centers for Disease Control and Prevention - CDC reports latest data on suicide behaviors, risk factors, prevention
U.S. Centers for Disease Control and Prevention - States must maintain or improve antismoking programs for further progress
U.S. National Cancer Institute - U.S. perspective on toxicology approaches for oncology drugs reviewed
U.S. National Institutes of Health - Brugia malayi immune evasion characterized
U.S. National Institutes of Health - Alcohol abuse up, but alcoholism down
U.S. National Institutes of Health - Interleukin 22 is a liver cell survival factor in murine liver injury models
Ullevaal University Hospital - VALUE study concludes angiotensin-receptor blockers can reduce blood pressure
Uniformed Svcs Univ of the Health Sci., Bethesda - Shigella flexneri mutant shows no attenuation of virulence
Univ. of California, Berkeley - Hepatitis delta virus ribozymes are controlled by a conformational switch
Univ. of California, Los Angeles - Carrier-added tracers highlight bone lesions during bone scans
Univ. of California, Los Angeles - PCOS more prevalent in Mexican-American women
Univ. of California, San Francisco - Folding of prion protein investigated
Universidad Autonoma de Madrid - Mobility of proteins restricted in polar regions of E. coli
Universite Paul Sabatier - Fission yeast strain expressing human CDC25A phosphatase developed
University Clinic, Essen - Mesohepatectomy is an alternate option to extended hepatectomy for liver tumors
University Hospital of Essen - Dopexamine modulates cellular immune functions during systemic inflammation
University of Aberdeen - Cancer care takes a toll on rural patients in Scotland
University of Alberta - Predictive factors for osteoporosis identified in patients Crohn disease
University of Berlin - Dacarbazine induces phototoxic dermatitis in malignant melanoma patients
University of Birmingham - Different promoter organizations produce different outcomes in bacteria
University of British Columbia - Monocyte recruitment to lungs characterized in pneumococcal pneumonia
University of California, San Francisco - Aortic smooth muscle cell expression of PKG-1 characterized
University of Chieti - Antioxidants decrease in girls who gain weight during valproate therapy
University of Cologne - SV40 DNA sequences are absent in primary central nervous system lymphomas
University of Colorado, Denver - Stem cell research leads to progress in engineering pancreatic islets
University of Connecticut - Kaposi sarcoma is a model for cancer immunotherapy
University of Connecticut - N-acetyl-cysteine promotes antiangiogenesis in orthotopic breast cancer
University of Connecticut - Tiotropium is anticholinergic for once-daily treatment of COPD
University of Dusseldorf - IDO degraded by the proteasome and NO has an effect on IDO protein stability
University of Edinburgh - Inadequate vaccines can help breed more vicious malaria strains
University of Edinburgh - Scottish study of deaths in drug injectors shows early help is critical
University of Essex - Factors affecting efficiency of immunoporation cell transfection identified
University of Florence - Italian-language questionnaire to detect dysfunction due to pain shows promise
University of Freiburg - Low intracortical inhibition shown by transcranial magnetic stimulation
University of Helsinki - IUD versus oral contraception study reveals equal acceptability rates
University of Iowa - Dysferlin involved in plasma membrane repair in muscular dystrophy
University of Miami - Genetics of type 1 diabetes reviewed
University of Michigan - Polarization mapping improves spectral analysis
University of Oregon - Proteins indicate link between G1 progression and mitotic exit
University of Ottawa - apoA-II regulates HDL stability and affects hepatic lipase association
University of Padua - Human T cell leukemia virus type 1 p13II negatively regulates cell growth
University of Saarland - Lipid optimization augments solid lipid nanoparticle-mediated gene transfer
University of Sao Paulo - Dipyridamole makes cisplatin more toxic to human larynx cancer cells
University of Sao Paulo - Immunity and immunosuppression in visceral leishmaniasis reviewed
University of Sao Paulo - No adverse lipid effects found in women 35+ using triphasic combined OCs
University of Sheffield - Age at diagnosis reflects disease stage and subsequent quality of care
University of Stellenbosch - Cyclosporine has limited long-term benefits in developing areas
University of Texas Southwestern - Patients with PD and high homocysteine levels may be more likely to be depressed
University of Tokyo - Microfluidic device developed for gas-liquid-solid hydrogenation reactions
University of Tubingen - Cloned transgenic animals produce high levels of antitumor bispecific antibody
University of Utrecht - Bone tissue engineering is feasible in critical sized defects
University of Virginia - Normalizing hemoglobin aids hemodialysis patients
University of Washington - Octagam is efficacious for treating primary immunodeficiency diseases
Walter & Eliza Hall Institute of Medical Research - Negative selection of semimature thymocytes characterized
Washington University - Diabetes and heart disease risk unchanged after liposuction
West Nile Virus - Bird in Knox County, Tennessee, confirmed to have West Nile virus
World Health Organization - Study highlights burden of environment on child health in Europe
Yale University - MEKK4 helps mediate STAT4-independent IFN-gamma production
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