Pharma Investments, Ventures and Law Weekly
Susan Hasty, Publisher
Table of Contents . . . September 5th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Pharma Investments, Ventures and Law Weekly | Other Publications
Advanced Viral Research Corp. - Third installment of $3 million dollars received for shares of biopolymer stock
Advancis Pharmaceutical Corp. - Pharmaceutical company reports loss of $0.37 per share
Aksys, Ltd. - Hemodialysis firm reports loss of $0.22 per share for second quarter
Alnylam Pharmaceuticals, Inc. - Pharmaceutical firm reports on IPO, financial results
Alpharma, Inc. - Pharmaceutical firm reports 5% decrease in revenues
Ambri Limited - Australian biotech firm reduces annual cash expenditure by 41%
Amylin Pharmaceuticals, Inc. - Pharmaceutical firm reports loss of $0.42 per share
Argonaut Technologies, Inc. - Pharmaceutical supplier reports 13% increase in sales
Array BioPharma, Inc. - Pharmaceutical firm reports quarterly loss of $0.12 per share
Atrix Laboratories, Inc. - Pharmaceutical firm reports 53% increase in revenue due to Eligard sales
Avera Pharmaceuticals, Inc. - Pharmaceutical firm raises $48M in Series C venture financing
Barr Pharmaceuticals, Inc. - Pharmaceutical firm announces stock repurchase program
Best Practices, LLC - Drug companies approach brand security issue head on, study shows
BioDelivery Sciences International - Biotech firm announces $4M credit facility
Biocom - California biotech community discouraged with state budget plan
!Chronimed, Inc. - Pharmaceutical firm loses Aetna contract
Abbott Laboratories - Government decides not to intervene and force down AIDS drug price
Academia Sinica - Novel electrode suitable for use in fMRI studies
Academy Mil Science - Lactating goat mammary glands act as protein synthesis bioreactors
Advanced Viral Research Corp. - Patient enrollment completed clinical trial of AVR118 in patients with AIDS
Albert Einstein College of Medicine - Liver-directed cell therapy is expected to augment organ shortages
Albert Einstein Medical Center - ACE inhibitor use may cause mouth swelling in patients
Alchemia Limited - Commercial manufacture of synthetic heparin on track after successful scale-up
American Council for Fitness & Nutrition - Group encourages journalists to play role in struggle against obesity
American Council on Exercise - Top mistakes people make in the gym listed by American fitness group
American Medical Systems Holdings - Device firm reports early physician experience with bladder repair system
Amgen Inc. - Aranesp receives positive regulatory opinion for extended dosing in E.U.
AngioDynamics, Inc. - Company renames laser venous system
Antares Pharma, Inc. - Vision system launched for use with human growth hormone in Japan
Applera Corp. - Celera announces clinical milestone payment from Merck
Asthma - Monitoring during pregnancy helps prevent serious exacerbations of asthma
Aurora Discovery - PicoRAPTR workstation introduced for labs
AusAm Biotechnologies, Inc. - Industry veteran Mark R. Straley joins Accumin maker as COO
Aventis - First influenza vaccine shipped to healthcare providers
Banyu Pharmaceutical Co. Ltd - Losartan improves glomerular structural changes in diabetic mice
Baylor College of Medicine - DC-SIGN domains essential for capture and transfer of SIV
Best Practices, LLC - Research finds pharma companies refine tactics to attract top investigators
Brigham & Women's Hospital - Tissue scaffolds ease drug and gene delivery to healing wounds
Business Update - Altria sees $25 million gain from accounting rule
Centre Hospitalier National Souro Sanou, Burkina F - Guillain-Barre syndrome strongly associated with HIV infection in young adults
Ceregene, Inc. - Gene therapy firm reports $32M Series B financing, provides pipeline update
Chang Gung University - CART peptide heightens mesolimbic dopaminergic neuronal activity
Charles University - High maternal age and low birth order increase risk of type 1 diabetes
Chiron Corp. - Company delivers first million doses of Fluvirin vaccine to U.S. distributors
Chiron Vaccines - NadA diversity and carriage in Neisseria meningitidis reviewed
Christie Hospital NHS Trust - Pluronic polymer-bound doxorubicin effective in phase I trial
Cleveland Clinic - Renal insufficiency and anemia increase mortality risk for CHF patients
Concord Hospital, Sydney - Heart attacks without chest pain more often fatal
Conforma Therapeutics Corp. - Two phase I studies of HSP90 inhibitor CNF1010 begin
Cornell University - ECG strain predicts morbidity and mortality in hypertensive patients
Cutting Edge Information - Study finds pharma companies spend 24% of marketing budgets on thought leaders
CytoGenix, Inc. - Company reports successful completion of preclinical antiherpes safety studies
DENTSPLY International, Inc. - Dental-products company increases earnings and sales
DOBI Medical International, Inc. - DOBI Medical International completes $5.16 million private placement
Dana Farber Cancer Institute, Boston - Major beta-thalassemia complications are primarily age-related in North America
Dicle University, Diyarbakir - Hepatitis B vaccine plus lamivudine did not eliminate viral DNA
Dietary Supplements - CRN encourages global harmonization in safety evaluation of dietary supplements
Drexel University - Elevated delta 15N is found in stream biota in areas with septic tank systems
Dutch Arthritis Foundation - Increased levels of blood markers seen years before onset of arthritis symptoms
Ecole Sup. de Phys. et de Chim. Industrielles - Web server provides variability analysis of DNA microarray data
Ehime University - Midkine promoter-based gene therapy decimates malignant glioma
Eksigent Technologies - Bruce Compton, PhD, named VP of chromatography operations
Emory University - Farnesyl transferase inhibitors show promise as therapies for breast cancer
Emory University, Atlanta - Novel software facilitates transcription factor binding site identification
Erasmus Medical Center - Antigenic and genetic evolution of influenza virus mapped
European Medicines Evaluation Agency - Agency highlights risk of adverse drug reactions arising from the use of SonoVue
EyeCare America - Pfizer commits $1.5 million to Glaucoma EyeCare Program
Federico II University, Naples - Management of diabetes in childhood reviewed
Food Allergy Initiative - President Bush signs bill that will benefit millions with food allergies
Forest Laboratories, Inc. - FDA approves Campral Delayed-Release Tablets for treating alcohol dependence
Forschungsinstitut fur Arbeitsmedizin - Genes may be a factor when toxic defense mechanisms decline with age
Fred Hutchinson Cancer Research Center - MOI determines proviral copy number in lentivirus-transduced repopulating cells
Fujita Health University - Aldose reductase inhibitor slows progress of diabetic nephropathy
Gartnavel Royal Hospital - Partial nephrectomy used to treat RCC arising in a live donor transplant kidney
Genentech Inc. - VEGF targeting of endothelial cells generates transient inflammation
Genetics Center of America - Neurodevelopmental disorders reported after thimerosal-containing vaccines
Georg Speyer Haus - Murine xenograft model of mycosis fungoides developed
Gilead Sciences, Inc. - Board of directors approves 2-for-1 stock split for pharma company
Given Imaging, Ltd. - Given Imaging reports first profitable quarter
HIV/AIDS - Women are forgotten HIV/AIDS patients in Zambia
Hartford Financial Services Group - Insurance company reports second quarter 2004 net income of $433 million
Harvard University - Leptin receptor signaling required for body weight homeostasis
Harvard University - Mechanoelectrical coupling may underlie triggered arrhythmogenesis
Healthcare Coverage - Rwanda to offer free generic drugs to HIV/AIDS patients
Hokkaido University - RNA interference against JC virus genes basis for infection control strategies
Holbeck - SeqExpress provides desktop visualization of gene expression
Hologic, Inc. - SecurViewDX breast imaging workstation receives FDA clearance
HomMed, LLC - Telemedicine company says shipments jumped 51% in first half of 2004
Huazhong Agricultural University - Microcalorimetric assay devised for B. thuringiensis protein yield
Huddinge University Hospital, Stockholm - NK cells stimulate proliferation of T and NK cells through 2B4/CD48 interactions
Imperial Coll. of Sci., Tech., & Medicine, Dublin - Mucosal vaccine against serogroup B meningococci developed
Inspire Pharmaceuticals, Inc. - Pre-IND meeting held with FDA for platelet aggregation inhibitor
Inst. of Nuclear Medicine & Allied Sciences, Delhi - Immunoconjugates improve targeting of photosensitizers
Institute Veille Sanitaire, Maurice - Education campaigns necessary as HIV transmission increases in Western Europe
Instituto de Investigaciones Biomedicas (IIB) - T3 and Triac inhibit leptin secretion and expression in adipocytes
John Radcliffe Hospital - Stroke research underfunded in Europe, perhaps the world
Johns Hopkins University - Scientists identify compounds that mimic calorie restriction
Karolinska Institute - St. John's wort increases extracellular dopamine in rat prefrontal cortex
Korea Advanced Inst. of Science & Technology - Cost-effective method devised for peptide microarray construction
Kos Pharmaceuticals, Inc. - Pharmaceutical company reports 85% increase in second quarter revenue
Kyoto University - Lentiviral transfection of dendritic cells upregulates alloreactive T cells
Kyowa Hakko Kogyo Company, Ltd. - Dipeptidyl peptidase IV inhibitor plus sulfonylurea improves glycemia
Kyushu Dent. College - Ozonated water is useful in reducing infections caused by oral microorganisms
Kyushu University - 2-Buten-4-olide is satiety substance increased in fasted state
Kyushu University - Soybean protein diet protects against methotrexate toxicity
Laboratoire Environnement et Chimie Analytique - SECM system using band microelectrode developed
Ligand Pharmaceuticals Incorporated - Pharmaceutical company announces 39% increase in second quarter total revenues
Louisiana State University - Once promising, fetal pulse oximetry questioned by many obstetricians
Manchester Royal Infirmary - Oral cancer study patients provide accurate self-reported smoking habits
McGill University, Montreal - No evidence found linking encephalopathy to pertussis vaccination
Medical Present Value, Inc. - Financial tool provider announces two payor contracts
Mental Health - Mentally ill losing services because of Los Angeles cuts
Meretek Diagnostics, Inc. - FDA clears POCone Infrared Spectrophotometer
Merit Medical Systems Inc. - Medical product manufacturer announces supplier agreement
Minneapolis VA Medical Center - Exercise heart rate recovery does not indicate quality of vagal function
Monash University - Testing of Alzheimer vaccines needed in non-murine models
Mt. Sinai School of Medicine, New York - Intentions and expectations may emerge within behavior-generating networks
Nakamura Gakuen University - Anti-obesity actions of mastication driven by histamine neurons in rats
Nat. Inst. for the Study and Cure of Tumors, Milan - Down-regulated survivin sensitizes human melanoma cells to topotecan
National Institute of Infectious Diseases, Tokyo - Expression of pertussis toxin S1 subunit protects against pertussis toxin
National Institute of Infectious Diseases, Tokyo - Reassortment with avian influenza virus attenuates influenza virus
Nektar Therapeutics - Therapeutics company announces increase in second quarter revenue
Nutra Pharma Corp - Biotechnology holding company funds RPI-78M in Multiple Sclerosis assays study
OAO Technology Solutions, Inc - EZ-CAP Product Suite add on evaluates performance of contracted physician groups
Orthovita, Inc. - Developer of orthopedic biomaterials reports second quarter 2004 results
Osaka City University - B7-1 gene transduction enhances immune response to metastatic tumor cells
PRAECIS PHARMACEUTICALS INCORPORATED - Pharmaceutical company reports second quarter results
PacificHealth Laboratories, Inc. - Nutrition technology company reports new study reports sports drink
Pain Treatment - New guidelines set for better pain treatment
Palo Alto Research Center - Enthalpy arrays developed
Pennsylvania Department of Health - Health Secretary reminds mothers about the benefits of breastfeeding
Pennsylvania State University - Culture, obesity stereotypes, self-esteem, and thin ideal investigated
PerkinElmer, Inc. - Life sciences company declares dividend, partners to study proteomics biomarker
Pertussis - Whooping cough cases increase in North Dakota
Pharmaceutical Profiles - Clinical development specialist reports the completion of a micro dosing study
Phytomedics Inc. - Biopharmaceutical company and ARC Ventures form Phytomedicinal Greenhouses
Point Therapeutics, Inc - Pharma company reports second quarter 2004 results
Precis, Inc. - Healthcare services company announces results
Primary Care Development Corp. - New York City clinics improve primary care for low-income patients
Procter & Gamble Co. - Enzyme inhibition aids collateral blood flow in ischemic animal models
Protein Design Labs, Inc. - Drug developer announces improved second quarter 2004 financial results
ProteoTech Inc. - Drug discovery company receives award from Institute on Aging
Prussian Private Institute of Technology - Computer program is used for predicting protein folding and structure
Psiron Ltd - Biotechnology company and ViroTarg sign anticancer license agreement
Psychiatric Solutions, Inc. - Behavioral health company announces financial results, new hires
Qiagen N.V. - Bioscience company reports financial results, provides business update
QuadraMed Corporation - Information technology vendor announces financial results
Quinton Cardiology Systems, Inc. - Cardiology systems producer named one of Washington's fastest-growing companies
Radiation Therapy Services - Radiation therapy provider reports second quarter 2004 financial results
Rice University - Evolvability could be a driving force in drug resistance
Robert Wood Johnson Medical School - Biofeedback helps asthmatics reduce steroid use
Royal Free & University College Medical School - Progress being made toward developing cytomegalovirus peptide vaccine
Ruhr University of Bochum - Constant-distance mode scanning potentiometric assay devised
Rush University - Low-temperature calcium phosphate surface enhances early implant fixation
SCOLR Pharma, Inc. - Pharma company files patent on asymmetrical multiple layered tablet
STAAR Surgical Company - Ophthalmic products producer reports second quarter results
Schneider Children's Med. Center Israel - Link between Guillain-Barre syndrome and hepatitis A vaccine reported
Scripps Research Institute - Matrix metalloproteinase-13 directs collagen during new vessel growth
Sensitech Inc. - Cooling equipment provider expands through European acquisitions
SeraCare Life Sciences, Inc. - Biological products manufacturer extends distribution alliance with Hitachi
Shamrock Structures, LLC - Proteomics company to provide services for Intra-Cellular Therapies
Shimane University - Gene expression from the fungus Bipolaris oryzae is analyzed
Sichuan Centers for Disease Control & Prevention - Method to measure radiation levels of building materials developed
Simulations Plus, Inc. - Software releases credited for company's Technology Fast 50 ranking
SinoFresh HealthCare, Inc. - Sinusitis, rhinosinusitis reclassified by task force as inflammatory diseases
Sorin SpA - European cardiovascular medical device group reports revenues up 6.5% in Q2 2004
Stanford University - Portions of brain are smaller in children born prematurely
Stanford University - Ultrasonic mixer devised for microfluidic channels
Stiftung Caesar, Bonn - tetR real-time PCR detects and quantifies tetracycline-resistant bacteria
Substance Abuse & Mental Health Services Admin. - Feds say "club drug"-related visits to ERs show some sharp declines
Sun Life Financial Inc. - Kevin J. Hart named president of insurance annuity distribution organization
Syntetech, Inc. - Chemicals company reports first quarter fiscal 2005 results
TGen - New prostate cancer gene identified
Tapestry Pharmaceuticals, Inc. - Cancer-focused pharmaceutical company reports second quarter 2004 results
Technical University of Dresden - Plant-derived hanatvirus virus nucleocapsid protein not immunogenic
Tenet Healthcare Corporation - Hospital company returns San Pablo hospital to West Contra Costa district
TeraRecon - College of Osteopathic Medicine enters agreement for portable ultrasound
Tercica, Inc. - Endocrine-focused biopharmaceutical company reports second quarter results
Tessera, Inc. - GTx collaborates to develop a diagnostic test to detect high-grade PIN
Texas A&M University - Adequate fluids and hydration are essential during prolonged exercise
The Equicom Group Inc. - Healthcare IT company signs RxPORTAL contracts with five existing customers
The Medicines Company - JAMA publishes long-term findings of REPLACE-2 angioplasty clinical trial
Thoratec Corporation - Medical device maker reports second quarter results
TolerRx Inc. - Biopharmaceutical company initiates clinical trial of TRX4 for psoriasis
Toshiba America Medical Systems Inc. - Diagnostic imaging company introduces cardiac CT imaging system at conference
Transkaryotic Therapies, Inc. - Biopharmaceutical company reports second quarter 2004 financial results
TriPath Imaging, Inc. - Cancer detection-focused company announces second quarter 2004 results
Tulane University - Erythropoietin is a potent booster of metallothionein gene expression
U.S. Centers for Disease Control & Prevention - Public beliefs about breastfeeding policies in various settings
U.S. Centers for Disease Control & Prevention - Retrospective of re-infection of humans with Plasmodium published
U.S. Centers for Disease Control and Prevention - Varicella vaccine reduces contagiousness of chickenpox
U.S. Department of Agriculture - Chronic stress regulates neuroendocrine responses in laying hens
U.S. Food and Drug Administration - Physician notification program launched for kids on antidepressants
U.S. MedSys Corp. - New company to supply products, services to diabetic Medicare community, others
U.S. National Cancer Institute - Drugs that manage angiogenesis slow renal cell carcinoma progression
U.S. National Institutes of Health - Ritonavir decreases nonrenal clearance of digoxin
U.S. National Institutes of Health - Transgenic mice show Notch signaling is important for synaptic plasticity
UFR Physiology of the Nutrition & Endocrinian Phar - Calamintha officinalis possesses hypoglycemic effect in diabetic rats
United Surgical Partners International, Inc. - Surgical group creates joint venture with Spanish investment firm
UnitedHealth Group - Completion of contested merger, receipt of approvals confirmed by health group
Univ. Medical Center, St. Radboud, Nijmegen - Spinal cord injury patients have preserved endothelial function in the legs
Univ. of California, Davis - Small-animal imaging gives cancer clues
Univ. of California, San Diego - Pediatricians overlook Kaswasaki disease in extremes of age ranges
Univ. of Texas, Dallas - Children with serious insect-sting allergies should get shots
University College London - Pain in the brain: It's not what you imagine
University Hospital Ulm - The glucose tracer FDG can't define breast cancer biology on PET
University of Alabama - CytB5 plays an important role in regulation of the androgen biosynthetic pathway
University of Alabama - YMDD aspartates of p66 are required and sufficient for RT polymerase function
University of Alberta - Superoxide dismutase mimetic may be cardioprotective alternative to estrogen
University of Baltimore - National report card shows states "failing" to check obesity
University of Birmingham - CD8+ T-cell immunity to cytomegalovirus reviewed
University of Bologna - Ankle morphology can be analyzed in large numbers for anthropometric statistics
University of Brescia - Pentraxin interactions with fibroblast growth factor stall angiogenesis
University of Calabria - Androgen-induced stimulation of prostate cancer requires estrogen receptor beta
University of California San Diego - Mobilization of antiretroviral SIV gene therapy vector is feasible
University of California, Davis - Abundant expression of granzyme A but not perforin in CD8+ cell granules in GALT
University of California, Los Angeles - alpha- and theta-defensins bind with high affinity to HIV-1 gp120
University of Cape Town - Fumonisin B-1 encourages liver disease and liver cancer formation
University of Cincinnati - Researchers show that PCN mediates tissue damage, necrosis during lung infection
University of Dundee - Human malaria parasite has distinct organelle-specific lipoylation pathways
University of Edinburgh - Atheroma of the aortic arch may be a factor in the etiology of stroke
University of Ferrara - Herpes simplex virus type 1 can infect cells via non-HSV-specific receptors
University of Florida - Prostaglandin E2 receptors up-regulated in peritoneal macrophages
University of Georgia - Fluids from lactobacillus cultures stimulate inflammatory factors in wounds
University of Giessen - Study: Neonatal cranial sonography in an important quality control tool
University of Groningen - Antisense oligonucleotides require effective delivery for optimal effects
University of Hohenheim - Artichoke pomace is a promising source of phenolic compounds
University of Hong Kong - Influenza causes excess hospital admissions in Hong Kong
University of Illinois - Beta-glucoside metabolism genes may be involved in biofilm formation
University of Illinois - Study reviews details of surgery for aortic arch thrombosis
University of Leipzig - A domain rotation in two distinct conformations is trapped by disulfide bridges
University of Medicine and Dentistry of New Jersey - University partners with drug company to launch health-focused software
University of Michigan - Effects of ventilation rate on instilled surfactant distribution determined
University of Michigan - Mexican Americans face far higher stroke risk than whites
University of Michigan - Phase change microvalve developed for integrated microfluidic devices
University of Milan - More research needed to expand treatment options
University of Milano Bicocca - Iron absorption is upregulated in celiac patients as a result of iron deficiency
University of Minnesota, Duluth - Use of size-selected DNA as templates for genome walking shows advantage
University of Navarra - Central retinal vascular occlusion by orbital pseudotumor studied
University of New South Wales - Genome-wide adaptation occurs without induction of oxidant defenses
University of Ottawa - IFN-gamma-induced inhibition of HIV replication mediated before virus entry
University of Paris - Recombinant Escherichia coli delivers genes to airway epithelial cells
University of Pittsburgh - Stem cell gene therapy produces regenerative bone protein in healing mice
University of Queensland - Antibody response by P. gingivalis and F. nucleatum modulated
University of Saarland - New approach has potential for screening of metabolic network activities
University of Sao Paulo - Study correlates angiographic aspects of ruptured plaque
University of Sydney - Impaired intercellular communication may cause deficient endovascular invasion
University of Turku - Interleukin-4 inaugurates HSV-based gene therapy in multiple sclerosis models
University of Utah - L-selectin is an effective marker for separating stem cells in the bone marrow
University of Vienna - Short- and long-term outcome of various stent types determined
University of Washington - HIV RNA higher in rectal mucosa than blood/seminal plasma independent of ART
University of Washington - Purifying selection masks mutational flexibility of HIV-1 reverse transcriptase
University of Zurich - A novel form of congenital disorder of glycosylation is identified
VIRxSYS Corp. - HIV-1-based vector used to develop mutants incapable of developing resistance
Valeant Pharmaceuticals - Pharmaceuticals company reports second quarter 2004 results
Valera Pharmaceuticals - Pharmaceutical company completes enrollment for phase 2 acromegaly drug study
Varian Medical Systems - U.S. FDA 510(k) clears new dose calculator for radiotherapy treatment plans
Velcura Therapeutics, Inc. - U.S. NIH awards nearly $1.5 million for study of human bone precursor cells
Ventracor Limited - Medicare increases payment for cardiac assist systems as permanent implants
Ventracor Limited - Notified body for CE marketing of artificial heart in Europe appointed
Veryan Medical, Ltd. - Breakthrough in treatment for kidney dialysis patients developed
Virgen del Rocio University Hospital, Seville - P. jiroveci polymorphisms suggest common infection source among disease type
Vital Images, Inc. - Imaging software company signs agreement for virtual colonoscopy applications
Vital Therapies, Inc. - Orphan drug designation granted for key component in liver assist program
Walter Reed Army Institute of Research - Vaccine protects mice against virulent Brucella melitensis
World Health Organization - Tuberculosis prevalence rates in China fall after DOTS introduced by WHO
Yale University - Sustained benefit of HAART lost when prisoners return to community
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