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Pharma Investments, Ventures and Law Weekly

Susan Hasty, Publisher

Table of Contents . . . November 7th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pharma Investments, Ventures and Law Weekly | Other Publications

Acuity Pharmaceuticals - Pharmaceutical company leapfrogs from seed funding to major milestones

Advanced Nutraceuticals, Inc. - Nutraceuticals company reports release of escrow funds

Allergy Therapeutics - Pharmaceutical company raises GBP 16M, seeks admission to AIM

Alltracel Pharmaceuticals PLC - Pharmaceutical company announces third quarter 2004 trading update

Amarin Corporation plc - Neuroscience company raises $12.75M in private placement

American Oriental Bioengineering, Inc. - Chinese biotech firm appoints independent director of company

AmerisourceBergen Corporation - Pharmaceutical services company projects earnings per share

AngioDynamics, Inc. - Medical device firm reports first quarter sales up 23%

Antisense Therapeutics Limited - Biotech firm to establish Level 1 American Depository Receipt program

BioProgress plc - Drug delivery systems provider raises funds via issue of convertible bonds

Bioaccelerate, Inc. - U.S. biotech invests in Australian cancer-focused company to widen collaboration

Biofrontera AG - Biotech firm strengthens drug pipeline by acquiring a phase II compound

Broad Institute - NIH funds first national SNP genotyping center

Cangene Corp. - Cangene reports earnings of 52 cents per share for fiscal 2004

Cellective Therapeutics - Forward Ventures invests in monoclonal antibody startup

Aalborg Hospital - Esophagus shear modulus of elasticity studied in rat model

Abbott Laboratories - Architect Systems' fertility menu enhanced with test for Estradiol

Active Pass Pharmaceuticals - Pharmaceutical firm receives grant from NIH for diarrhea drug development

Acuity Pharmaceuticals - Drug firm closes $15M financing, initiates trial of RNAi therapeutic

Addiction Medicine - U.S. HHS awards grants to treat co-occurring substance abuse/mental disorders

Advanced Neuromodulation Systems, Inc. - Device firm withdraws $22 per share Cyberonics proposal

Aerogen, Inc. - Device companies announce distribution agreement for nebulizer system

Akzo Nobel - Pharmaceutical company divests its Resins business

Allos Therapeutics - Brain metastases patients' radiographic response at 3 months predicts survival

American Academy of Allergy, Asthma and Immunology - Allergy academy presents Samter Journalism Awards for health, medical reporting

American Psychological Association - APA applauds passage of Mentally Ill Offender Treatment and Crime Reduction Act

Animal-Borne Disease - New laboratory provides key research into animal diseases

Antares Pharma, Inc. - Phase III trial update provided on Bio-E-Gel

Applera Corp. - Court dismisses Promega's case against Applied Biosystems and Roche

Argos Therapeutics, Inc. - Company changes name and prepares for HIV vaccine trial

Artemis Pharmaceuticals GmbH - Cooperation, license agreements signed related to mouse genetics

Australian National University - Auditory brainstem neurons characterized in novel murine model

Auvergne University - Impaired muscle protein synthesis linked to S6K1 dysregulation

Aventis - Thirty million doses of influenza vaccine shipped to healthcare providers

Axonyx Inc. - Biopharmaceutical company announces appointment of new director

Bariatric Surgery - Obesity surgery can cure diabetes, high blood pressure and other ills

Barr Pharmaceuticals, Inc. - Tentative approval granted for generic version of Femhrt tablets

Baylor College of Medicine - Mechanisms of perineural invasion elucidated

Beijing Institute of Radiation Medicine - Estrogen receptor alpha genotypes associate with susceptibility to hepatitis B

Biofrontera, AG - DNAPrint genomics to acquire majority ownership in German pharmaceutical company

Boehringer Ingelheim Pharmaceuticals, Inc. - Pharmaceutical company offers its alternative to recalled arthritis medication

Brandeis University - Morning and evening clocks identified

British Columbia Cancer Research Centre - Role of lipid rafts in immunological synapse determined

CCCompany - Web portal launched helps clinicians track progress in drug therapies

CIMOT - Antinuclear antibody absorption by hepatitis B vaccine warrants evaluation

Canada West Biosciences Inc. - CGE-LIF cycling probe technology analyzes small samples for genomic DNA

Carnegie Mellon University - Interactive video behavioral intervention reduces adolescent females' STD risk

Case Western Reserve University - Cleveland stem cell investigators awarded $3.1 million

Catherines Plus Sizes - Plus-size retailer raises funds to fight breast cancer

Catholic University of the Sacred Heart - Vascular dysfunction may be responsible for age-related hearing loss

Cell Therapeutics, Inc. - Study results of treatment for leukemia with arsenic trioxide presented

Chinese Academy of Science - In preeclampsia, intermediate trophoblasts don't express MCAM/CD146

Chinese University of Hong Kong - ACE inhibitors increase survival in Chinese type 2 diabetic patients

Chlorogen, Inc. - Agreement inked to produce first-ever products from chloroplasts

Cleveland Clinic Foundation - Several options available for incontinence management

Clinique Notre-Dame - Laparoscopic cystogastrostomy safe and effective

Cntr. for Research on Reproduction & Women's Hlth. - Gene profiles illuminate the polycystic ovary syndrome theca cell phenotype

Cook, Inc. - FDA approves medical device to treat AAA

Cornell University -  Listeria monocytogenes tracked in cheese processing plants

Cozart, plc - Drug-testing company expands operations with move to new facilities

Croatian Veterinary Institute, Zagreb - Porcine circovirus type 2 from pigs was in Croatia detected and characterized

Dana-Farber Cancer Institute - Fertility concerns affect treatment decisions of many young women with cancer

Dokuz Eylul University, Izmir - HLA haplotypes associated with myasthenia gravis

Dor Yeshorim - Ashkenazi Jewish patients with glycogen storage disease Ia bear R83C mutations

Duke University - Angiogenesis therapy successful for artery disease

Duke University Medical Cntr. - Slightly increased risk of ischemic stroke found with tamoxifen

Efoora, Inc. - Diagnostics company appoints new chief financial officer

Ehime University - Dendritic cells in chronic hepatitis C patients alter immunological response

Elekta - IMPAC enters sales consulting agreement

Eli Lilly and Company - Prior fractures are predictors of future fractures in women with osteoporosis

Emory University - Debate-guidelines for glycopeptide-resistant enterococci control have not worked

Encore Medical Corp. - Acquisition of Empi, Inc., completed by orthopedic device company

Encysive Pharmaceuticals - Data on Thelin presented at American College of Rheumatology Meeting

Enhance Biotech, Inc. - Recruitment begins for phase III trial for premature ejaculation compound LI301

Environmental Health - Group seeks to bring clean water to millions

Enzo Biochem, Inc. - Positive phase II data reported for Alequel

Evanston NW Healthcare - FAS regulates oncogenic proteins closely related to malignant transformation

Fine Fragrances and Cosmetics - Maker of skin lightening creams responds to TV statement on product dangers

Food Allergy & Anaphylaxis Network - Food allergy group calls for standardized guidelines and training in schools

Forbes Medi-Tech, Inc. - Cardiovascular-focused biopharma appoints new CFO

GENETIX Pharmaceuticals, Inc. - Company raises $12 million to fund gene therapy

GTx, Inc. - Timothy R.G. Sear named to board of directors of men's health company

Gary Marsh - Health officials brief families on Pratt & Whitney cancer study

Genaera Corp. - Company wins phase I SBIR grant for obesity program

Genaera Corp. - U.S. FDA gives fast-track status for antiangiogenic

Generex Biotechnology Corp. - Dr. Eric von Hofe named VP for product development and scientific affairs

Genetic Technologies Limited - Biotech signs agreements with MetaMorphix for animal genetics patents, rights

Given Imaging - Italy's Piemonte region to reimburse for PillCam SB Endoscopy

Goteborg University - Greater risk for children of mothers over 40 to die in utero or as a newborn

Goteborg University - People often infected have poor immune response to Neisseria vaccine

Guava Technologies - Gianfranco de Feo, PhD, named director, customer support and service

Guy's, King's, & St. Thomas' Hospital, London - CCR5-targeted SIV vaccination strategy prevents or inhibits SIV

HIV/AIDS Treatment - Africans give their governments poor marks on evaluation

Hacettepe University, Ankara - Sphingolipidoses are relatively common and important health problem in Turkey

Haukeland University Hospital, Bergen - Human endothelial cells from different types of vasculature warrant study

Helsinki University - Effect of early vs. late prehospital thrombolysis studied in acute MI

IMPAX Laboratories, Inc. - Pharmaceutical company announces effectiveness of registration statement

INSERM, UMR 554, Montpellier - Protein binding sites attractive drug target for TCL1 protein-caused leukemia

Imperial College London - Flight simulators for pilots offer treatment for chronic dizziness

Indiana University - Placement in retained roots does not cause inflammation in baboons

Influenza - Experts: Good hygiene can ward off flu

Institut fur Medizinische Parasitologie, Bonn - Two spermidine analogues show moderate in vitro inhibition, ineffective in vivo

Institute Microbial Technology - CTL epitopes predicted using QM, SVM, and ANN techniques

Instituto Oswaldo Cruz - Antibodies to P. vivax protein studied in malaria-exposed subjects

Japan National Institute of Neuroscience, Tokyo - BM-derived SP/Mac-1low cells play an important role in muscle regeneration

Johns Hopkins University - Single postoperative measurement can estimate myocardial cell injury

Johnson & Johnson Pharmaceutical R & D LLC - Minute doses of JNJ-17029259 enhance the utility of standard chemotherapy

Kaohsiung Medical University - TNF-alpha/soluble receptors ratios prognostic in oral squamous cell carcinoma

Karolinska Institute - Mobile phone use increases acoustic neuroma

Karolinska University Hospital - glomerulopathy progresses in normoalbuminuric patients with diabetes

Kuwait University - PCR-RFLP detects ethambutol-resistant Mycobacterium tuberculosis strains

Kyushu University - VEGF is a key mediator of angiotensin II-induced vascular inflammation

LAB International Inc. - Inhalation drug company secures new funding

LabOne, Inc. - Cytyc Corp. announces a multiyear agreement for ThinPrep Imaging System

Laboratory of Physiological Medicine, Besancon - Short-term heart rate variability depended upon the type of exercise

Laikon General Hospital, Athens - MRI technique is a reliable method for assessing deposition of iron in the liver

Latch, So & Hwang Chiropractic - Chiropractors cite alternatives to antidepressants for pain-related depression

Lek - New drug designed to reduce cholesterol levels launched

LifeAssays Inc. - Swedish company presents mass screening tests at investment conference

LifeCycle Pharma A/S - Clinical trials slated for choelsterol drug

Logical Images - District of Columbia EHMSA licenses VisualDx diagnostic software

London School of Hygiene & Tropical Medicine - MMR vaccination not associated with developmental disorders

Los Alamos National Laboratory - Molecular mechanisms of ATRA in APL determined

Louisiana State University - trans-Expressed PC1 propeptide acts as PC1 inhibitor

Lund University - Polycation-mediated precipitation captures plasmid DNA from alkaline lysate

Lynx Therapeutics, Inc. - Genomics company announces gene study in human embryonic stem cells

Magistral Biotech, Inc. - Canadian biotech company begins two studies on cholesterol combination therapy

Massachusetts General Hospital - Function of Rit42 protein elucidated

Massachusetts General Hospital - Infantile hemangioma endothelial cells arrest at an early developmental stage

Matritech, Inc. - Cancer diagnostic company announces new research and development executive

Mayo Clinic - Mycophenolate mofetil is effective for managing non-renal lupus

Mayo Clinic - New approach to treating inflammation of the arteries developed

McGill University - Step on it! Fast walking after stroke improves mobility

McMaster University, Ontario - Viral subunit protein plus CpG ODN protects against HSV-2

MedImmune Vaccines Inc. - Microneutralization assay using cytomegalovirus strains developed

Medical University of Warsaw - Nosocomial meningitis outbreak caused by Acinetobacter baumannii

Medical University, Lublin - Cerebrospinal VEGF may protect amyotrophic lateral sclerosis patients' neurons

MedicalCV, Inc. - Gary O. Tegan joins device maker as VP, marketing

Medtronic Inc. - Long-term monitoring of SvO2 by implanted devices may be feasible

Merck & Co., Inc. - Pharma company elects member to board of directors

Merck Research Laboratories - Study of influenza virus A M2 peptide conjugate vaccines conducted

MicroMRI - SBIR grant for bone imaging technology may help patients with osteoporosis

MitoChroma Research, Inc. - Pharma development company discovers potential treatment for type 2 diabetes

Monash University, Melbourne - Maternal cigarette smoking could impair arousability from sleep in infants

Murdoch University -  Brachyspira hyodysenteriae lipoprotein protects pigs from dysentery

NASA - Newfound star cluster may be final Milky Way "fossil"

NCRIC Group, Inc. - Healthcare financial services organization announces resignation of COO

Natl. Inst. of Advanced Science & Tech., Saga - Novel techniques improve control of macromolecular reactions

Natl. Inst. of Medical Science, Mexico - Oral contraceptives, IUD produce same risk of disease flares in women with SLE

Natus Medical Inc. - Agreement signed with HealthTrust Purchasing Group for newborn hearing screeners

NeoPharm - Biopharma company announces update on trial of compound for advanced cancers

Nippon Shinyaku Co. - Pharma company and IVAX conclude license agreement for anticancer agent

Novartis Consumer Health, Inc. - New ranking names America's cough and cold capitals

Nucleonics, Inc. - Biotechnology company files a request of re-examination of Benitec

Obesity - America finally holds line on weight, market survey says

Ohio State University - Gene therapy overcomes blood-brain barrier to treat CNS manifestations

Oklahoma State University - Biogenic amines and bacteria analyzed in recalled canned anchovies

Oklahoma State University - Influenza B virus lacks sequence homology to influenza A virus antigenic sites

Oncology - HCA and Tennessee Oncology form Sarah Cannon Research Institute

Orthopedics - Better foot motion after heel fracture is priority for patients

Our Lady's Hospital for Sick Children, Dublin - Chromosome 11q loss characterizes a unique subset of neuroblastoma

Ovarian Cancer - High-risk women recruited for studies via mass mail worry less about testing

P&G Pharmaceuticals - Women with osteoporosis treated with Actonel have good bone mineralization

Pacificare Behavioral Health - New study looks at matching patients with correct amount of depression therapy

ParAllele BioScience - Biosciences company enters collaboration to study genetics of heart disease

Performance Health Technologies Inc. - Computer-based rehab developer invents neuromuscular re-education system

PharmaMar - Pharma company presented six studies at cancer therapy conference

Power3 Medical Products, Inc. - NYU Medical Center begins validation study on early detection breast cancer test

Prime Clinical Systems - Technology company releases report generation for it practice management system

QuadraMed Corporation - Hospital group selects acuity, productivity, benchmarking software system

ReGen Biologics, Inc. - Orthopedic products company presented technology overview at conference

RiboNovix, Inc. - Biotech company working to address problem of antibiotic resistance

Roche - FDA grants priority review to Pegasys with Copegus for HCV in HIV patients

Roslin Institute - Transgenesis could make chicks viable models for genetic research

Royal Children's Hospital, Melbourne - Gluten-free diet improves growth in diabetics with celiac disease

Royal Philips Electronics - Electronics company announces partnership, 500th installation of CardioMD

Sahlgrenska University Hospital - If bile level is kept low, intrahepatic cholestasis doesn't pose risk to fetus

San Filippo Neri Hospital, Rome - Acute right insular damage may lead to a derangement of cardiac function

Santarus, Inc. - Drug developer launches immediate-release oral proton pump for gastro diseases

Savient Pharmaceuticals, Inc. - Jeremy Hayward-Surry named board chair by drug developer, manufacturer

School Nutrition - USDA gets creative to make school lunches healthier

Scientific American Magazine - Science magazine hosts discussion of debate on embryonic stem cell research

Serono - Nurse system available for U.S. patients with multiple sclerosis

Shimane Medical University - KiSS-1 downregulation causes tumor invasion/worse prognosis in gastric cancer

Shinshu University - Triiodothyronine increases lipogenic enzyme expression and triglyceride deposits

SinusPharma, Inc. - Phase 1 clinical trial for intranasal delivery of antibiotic initiated

Sirtris Pharmaceuticals - Pharmaceuticals focused on metabolic disease announces directors, advisors

Spectranetics Corporation - Laser products utilized during live case sessions at transcatheter convention

St. Jude Children's Research Hospital, Memphis - Sendai virus vaccine is safe and immunogenic in healthy adults

Staffordshire University - Exercise does not affect circulating angiotensin-converting enzyme

Stanford University - Stanford to test effects of drug widely used for pediatric hypertension

Stem Cell Research - IFATS researchers believe fat stem cells may offer therapeutic potential

Stressgen Biotechnologies - Biotech company files Canadian preliminary prospectus for common share offering

Summa Health System - Study finds portion control best diet plan

Synthematix, Inc. - Chemistry-focused software developer expands facilities, names division heads

TNS Media Intelligence/CMR - Online survey shows restaurants struggling to keep dieting customers

Tapestry Pharmaceuticals, Inc. - Anticancer compound inhibits growth in drug resistant cell lines, company says

Target Software, Inc. - Software developer installs mobile sales systems for Watson Pharmaceuticals

The Scripps Research Institute - Research institute appoints researcher specializing in nervous disorders

Thuris Corporation - Company formed to market medical device for central nervous system diagnosis

Tor Vergata University of Rome - Novel assay improves diagnosis of myotonic dystrophy type 2

Trafalgar Ventures, Inc. - Cyberkinetics merger complete

Transition Therapeutics Inc. - Therapeutics company sells subsidiary to Neurogenesis Biotech

Triathlon Medical Ventures - Investor group closes new $96 million Midwest-based life sciences venture fund

Tuberculosis - Harris County, Texas, tuberculosis testing, treatment under state review

TurboWorx, Inc. - University of Illinois at Champaign-Urbana selects distributed computing systems

Turku University - Colic infants do not have abnormal autonomic reactivity to stimuli while asleep

U.S. Air Force - Patient knowledge of allergy immunotherapy better than expected

U.S. Food & Drug Administration - Helical forms of peptides determined by NMR and molecular dynamics

U.S. National Institutes of Health - P-glycoprotein rapidly regulated at the blood-brain barrier by endothelin-1

U.S. National Institutes of Health - Yeast prions not involved in transcriptional activity

Uludag University - Negative pressure wound therapy promotes diabetic foot ulcer healing

Univ. of British Columbia - Met-dependent signaling goes through progressive changes in cancer model

Univ. of California, Davis - Emerging food technology and world health reviewed

Univ. of California, Los Angeles - Genetic profiling links key genes to alcohol-related expectancies

Universidad de Sevilla - Saccharide-directed delivery to biological receptors optimized

University Clinic of Saarlandes - Biphasic cardioversion allows comparable success rates with lower energies

University College London - Avodart offers improvements in quality of life for men with prostate problems

University Hospital, Mannheim - Micelle delivery of doxorubicin increases cytotoxicity to prostate cancer cells

University Medical Center, Rotterdam - Rates of advanced breast cancer lower in The Netherlands due to mammography

University of Alabama - Dietary n-3 fatty acids do not improve exercise performance

University of Alberta - Periurethral and transurethral injections of bulking agents effective for SUI

University of Bristol - The acute response to islet PPAR gamma overexpression is insulin resistance

University of British Columbia, Vancouver - arsC genes identified/quantitated in environmental samples by real-time PCR

University of California San Francisco - Omomyc expression in the skin prevents Myc-induced papillomatosis

University of Catholique Louvain - Leptin increases adiponectin but barely decreases resistin

University of Chicago - Lung image database consortium established for medical imaging researchers

University of Copenhagen - LV systolic dysfunction was a strong predictor of mortality and morbidity

University of Erlangen Nurnberg - Healthy women need better understanding of disease incidence, risk factors

University of Erlangen-Nurnberg - Treatment strategies in patients with chronic renal disease outlined

University of Florida - Researchers reveal secret lives of genes during spinal injury

University of Florida - Scientists have bionanotechnology recipe to find elusive bacteria

University of Florida - Superoxide dismutase gene transfer may treat complex I deficiency disorders

University of Genoa - 5-HT treatment may attenuate glutamate efflux during brain ischemia

University of Glasgow -  Vibrio cholerae proteinases characterized

University of Groningen Hospital - Chimeric constructs target heterologous genes in cancer-derived cells

University of Helsinki - Release kinetics of Egalet constant-release system determined via scintigraphy

University of Idaho - Past shows Mount St. Helens ash poses minimal health threat

University of Illinois - Soy isoflavones in food, rather than pure form, better for ER-dependent disease

University of Lausanne - Endogenous angiotensin II promotes induction of vulnerable plaques

University of Leeds - Herpesvirus-based vector guides fusion protein to cancer cells

University of Leeds - Packed cell volume is important in determining orthostatic tolerance

University of Liege - Strontium ranelate may reduce fractures in older women

University of Madrid - HIV-1 immunogen vaccine plus antiretrovirals promotes virologic control

University of Maryland - Incidence of severe malaria useful as endpoint for vaccine trials

University of Massachusetts - Analysis of CAP, Cbl, and CrkII role in insulin-regulation of GLUT4 performed

University of Massachusetts - Insulin resistance reduces carbohydrate utilization during exercise

University of Massachusetts - Poxvirus protein N1L inhibits NF-kappa B and IRF3 signaling

University of Michigan - Levels of fibroblast growth factors significantly lower in depressed people

University of Michigan - Restoration of metastasis suppressor genes could abate cancer dissemination

University of Michigan - Use of substance honed to improve lung function in premature infants

University of Milan - The effects of broad band electromagnetic fields on HSP70 appear to be biphasic

University of Minnesota - Novel method measures knowledge of prostate cancer screening risks/benefits

University of Minnesota - Surgical treatment for obesity appears effective for weight loss

University of Naples - Review finds recombinant FSH is more effective therapy for inducing ovulation

University of Newcastle - Community-based research shows mixed therapy regimens in an Australian suburb

University of North Carolina - Study describes basic mechanism in cell growth control involving damaged DNA

University of Oklahoma - Ephedrine linked to sudden cardiac death

University of Oklahoma - Second-generation thiazolidinediones and hepatotoxicity reviewed

University of Puerto Rico - ECM-integrin interaction appears to play role in regenerative process

University of Rochester - Touching research: How white blood cells navigate

University of St. Etienne - Questionnaire is sensible and valid for estimation of daily energy expenditure

University of Stuttgart - Proteins involved in CFTR degradation identified

University of Tokyo - RNA splicing factor SF3a66 also acts as microtubule-bundling protein

University of Tubingen - Multiresistant Acinetobacter baumannii outbreak occurred in surgical room

University of Utah - Abnormal homocysteine metabolism not key factor in autoimmune disorder

University of Valencia - Program improved management of patients hospitalized for heart failure

University of Wisconsin - Intrapulmonary arteriovenous shunting occurs during exercise in healthy humans

University of York - Study will look at how professionals approach the complex ethics of IVF

Urinary Incontinence - Bladder injuries detected cytoscopically during transobturator sling procedure

Ventracor, Ltd. - Company addresses possible reimbursement for VentrAssist LVAS

VivoMetrics - LifeShirt System measures cardiopulmonary parameters in breast cancer study

Washington University, St. Louis - System may aid therapies to lower incidence of acute coronary artery diseases

Weill Medical College - Prescriptions for antibiotics to prevent anthrax now uncommon

Western Media Group Corporation - Medical services company launches new Web site

Yale University - Melanin makes skin vulnerable to harmful ultraviolet rays

ZONARE Medical Systems, Inc. - Medical device company names Davidge VP-CFO, Terranova VP of operations

eResearchTechnology, Inc. - European pharmaceutical awards $1.3M for electrocardiographic services

pSivida Limited - Data analysis confirms BrachySilTM is safe and effective at tumor regression

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