Susan Hasty, Publisher
Table of Contents . . . December 26th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Pharma Investments, Ventures and Law Weekly | Other Publications
Acambis plc - Pharma company releases third quarter 2004 results
Access Pharmaceuticals, Inc. - Pharmaceutical company reports loss of $0.16 per share
Alchemia Limited - Pharma company discusses financial results
Amgen, Inc. - Biotech company announces offer of $2B in two series of senior notes
Antares Pharma, Inc. - Pharmaceutical firm reports loss of $0.06 per share
Astralis, Ltd. - Biotech company reports loss of $0.02 per share
Australian Cancer Technology - Australian biotech firm confirms fundraising
Baxter International, Inc. - Pharmaceutical firm declares annual dividend
BioDelivery Sciences International - Biotech company reports first quarterly profit of $0.14 per share
BioMS Medical Corp. - Pharmaceutical firm reports loss of $0.05 per share
BioTime, Inc. - Biotech company reports 55% increase in revenues
BioVeris Corporation - Diagnostics company reports $1.71 per share quarterly loss
Bioenvision - Oncology company added to NASDAQ Biotechnology Index
Bioniche Life Sciences, Inc. - Canadian biotech firm's revenues increase in 1Q of fiscal 2005
Bone Care International, Inc. - Pharmaceutical company added to NASDAQ Biotech Index
Aarhus University Hospital - Calcitonin gene-related sensory neurons lost in early diabetes
Accumed Systems, Inc. - SBIR grant awarded for development of diagnostic catheter system
Affymetrix, Inc. - Firm launches comprehensive array offering for microbiology research
Akorn, Inc. - Agreement signed for Calcium-DTPA and Zinc-DTPA
All India Institute of Medical Sciences - Insulin resistance and C-reactive protein in Indian adolescents studied
Alzheimer Association - Survey shows brain and memory health second greatest health worry
Alzheimer Disease - Neurosciences center patents two potential Alzheimer treatments
American Society for Reproductive Medicine - Position statement on donor suitability after smallpox vaccination released
Angiolink Corporation - Medical device company acquired by Medtronic
Arizona State University - Novel blood gas sensors combine microdialysis and optical monitoring
Awards - HealthAmerica and HealthAssurance employee receives Breath of Life Service Award
Ben Gurion Univ. of the Negev - Predisposing factors with normal female anatomy include genetics, behavior
Biocon Limited - Partnership signed to discover and develop therapeutic antibodies
Biogen Idec - Faheem Hasnain named as senior VP at biotech company
Boehringer Ingelheim - Interim results reported from second phase III study of tipranavir
Boston Scientific Corporation - Taxus data presented at American Heart Association meeting
Bovie Medical Corporation - Electrosurgery device maker reports record revenues, net earnings
Breast Cancer - Cancer drug risk equal for black, white women
Brigham and Women's Hospital - Endothelial phenotype of susceptible and resistant vasculature characterized
CNRS, Villejuif - Functionally critical residues of the type I human interferon receptor
Cancer Research UK - Xenograft response to cisplatin can occur regardless of p53 status
Cardiac Science, Inc. - City of Miami selects provider of AEDs
Cardiac Science, Inc. - Distribution agreement expanded for Powerheart AEDs to hospitals
Center for Investigational Farming, Cumana - Paralytic shellfish poisoning outbreak caused by Gymnodinium catenatum
Charite Universitatsmedizin Berlin - Aspirin and clopidogrel are indicated for patients with acute coronary syndromes
Charite-Universitatsmedizin Berlin - Small-molecule insulin mimetic reduces hyperglycemia and obesity
Children's Hospital of Wisconsin - Experimental rabies treatment sees success
Chinese Univ. of Hong Kong - DNA microarray expression profiling predicts chemotherapeutic response
Christie Hospital, Manchester - Continued growth hormone treatment after final height needed
Chromos Molecular Systems, Inc. - Cellular engineering company reports quarterly loss of $0.12 per share
Cincinnati Children's Hospital - Arginase may play key role in asthmatic responses
City of Hope Medical Center - New cell therapy can make HIV its own worst enemy
Cleveland Clinic Foundation - Abciximab does not enhance effect of reteplase on ST-segment elevation
CollaGenex Pharmaceuticals, Inc. - Patient enrollment for phase III study of Periostat completed
Columbia University - Researchers honored for work on signal transduction in cells
CompuMed, Inc. - Company seeks patent for use of OsteoGram for digital mammography
Crucell N.V. - Edwards Lifesciences enters PER.C6. research license agreement
Current Technology Corp. - ETG treatment center opens in Singapore
DOR BioPharma, Inc. - Maker of orBec reports Q3 net loss of $1,406,411
Dade Behring, Inc. - Bradley G. Pattelli resigns from board of diagnostics company
Dana Farber Cancer Institute - AHSCT favorable for relapsed/refractory acute promyelocytic childhood leukemia
Dartmouth Medical School - $1.6 million grant will fund children's clinic in Tanzania
Debrousse Hospital, Lyon - Busulfan good alternative to TBI to improve quality of life in childhood ALL
Decision Resources, Inc. - Analysis: Marketing muscle will be a major factor in the success of Lamictal
DiaSys Corp. - Diagnostics company enters Costa Rican market
Duke University - Low VEGF levels in ischemic flaps warrant the use of exogenous protein
EPIX Pharmaceuticals, Inc. - Dyax announces second peptide discovery collaboration
Eiffel Technologies Limited - Drug re-engineering company signs material transfer agreement
Elephant Pharmacy - Wellness pharmacy announces financing and unveils growth plans
Emory University - Doppler PVD may better select responders to cardiac resynchronization therapy
Emory University - NADPH oxidase could be targeted for the treatment of cancer or heart disease
Enzo Biochem - Amplification technology launches for gene expression analysis studies
Enzon Pharmaceuticals, Inc. - Arthur J. Higgins to step down from board of directors at pharma firm
Erasmus Medical Center, Rotterdam - Sirolimus-eluting stent implantation in octogenarians appears to be feasible
Evanston Northwestern Healthcare - Evanston, Illinois healthcare system launches online patient access service
Fairfax Identity Labs - Commonwealth Biotechnologies acquires DNA-profiling company
Family Policy Council - Top family council community networks recognized in Washington State
Female Sexual Dysfunction - Professional group calls for clinical guidelines on androgen therapy
Fischer Imaging Corp. - Imaging company reports 53% increase in revenue
Fukui University - Vertical orientation of acetabular component affects stability and wear
Genitope Corp. - Company provides update on MyVax Personalized Immunotherapy
Grant Life Sciences, Inc. - Oncology diagnostics company names David Bolick, MD, as chief medical director
Grants - Dartmouth ends foundation with $1.6 million grant
Grants - Grant helps children learn about nutrition
Gyeongsang National University - Novel immunoassay developed for detection of ochratoxin A in food
HEE Corp. - Diabetes company to discontinue effort to acquire Halstead Hospital
Hacettepe University, Ankara - Novel microporous scaffolds use supercritical CO2 for bone tissue engineering
Hadassah University Hospital - Gene expression in rat bladder cancer models shadows that of humans
Harvard University - JAGGED1 expression is associated with prostate cancer metastasis, recurrence
Harvard University - Study findings indicate seafood intake during pregnancy may reduce fetal growth
Hemispherx Biopharma, Inc. - Alferon maker reports stockholders' equity increases approximately 146%
Hopital Purpan, Toulouse - Simian virus 40 not involved in lymphoma pathogenesis
Hopital St. Louis, Paris - Infrared radiation affects apoptosis mitochondrial pathway in human fibroblasts
Hospital Germans Trias i Pujol - Pneumococcal bacteremia in children in Barcelona reviewed
IHS Bioceuticals, LLC - Clinical studies show natural treatment aids arthritis patients
INSERM, Paris - Differential effects of agomelatine versus fluoxetine in the rat brain
Imperial College London - Drinking water could be beneficial to patients with low blood pressure
Imperial College School of Medicine - MRI-guided US therapy relieves symptoms in patients with uterine fibroids
Indiana University - Novel pyridostigmine analogs show promise as AChE imaging agents
Influenza Vaccine - Healthy elderly urged to skip flu shots
Innsbruck Medical University - Complement receptor type 3 increases productive HIV-1 infection of DCs
Inpharmatica Ltd - Shionogi & Co. Ltd. signs Biopendium Online subscription
Institute for Research and Development - A possible ancient origin for tuberculosis found in Casablanca
Institute for Systems Biology - Innovative technology leads to new insights on carcinogenesis
Institute of Medicine - U.S. women with HIV lack access to healthcare
Intarcia Therapeutics Inc. - Pharmaceutical company raises $50 million in Series E financing
Ipsogen - Companies to offer pharmacogenomic technologies for oncology drug development
Johnson & Johnson Pharmaceutical R&D - Transcriptional response to CRF characterized in mouse pituitary cells
Kaohsiung Medical University Hospital - Multiple factors affect quality of life for male HIV/AIDS patients on HAART
King Edward Memorial Hospital & Research Center - Obesity problem in India may have intrauterine origins
Kyushu University - Protein tyrosine phosphatase inhibitor hastens angiogenesis in ischemic limbs
Leiden University - Pentoxifylline reduces fibrin deposition in neonatal hyperoxic lung injury
Los Alamos National Laboratory - Method to predict impact of nonsterilizing vaccine against HIV developed
MFIC Corporation - Microfluidizer equipment producer announces significant new orders
Maastricht University - Cannabis increases risk of psychosis
Mario Negri Institute for Pharmacology Research - Overexpressed neuropeptide Y may protect against hyperexcitability
Marmara University - Melatonin protects against diabetic changes in rat aorta
Massachusetts General Hospital - Gene-modified stem cells prevent type 1 diabetes in murine models
Max Planck Institute, Hamburg - MARK/PAR1 kinase regulates microtubule-dependent transport in axons
Mayo Clinic - Risk factors for beta-blocker therapy failure identified
MedAire - Health and security solutions provider names president
MedCath Corporation - Cardiovascular disease healthcare provider releases financial results
MedCom USA, Inc. - HIPAA compliant point-of-sale terminal now available in Georgia
Medical College of Georgia - Finding could improve safety of stem cell transplants
Medical Imaging - Kodak gets U.S. FDA approval for mammography system
Medical Research Council - Study reinforces effectiveness of spinal manipulation
Medical University of Vienna - Serum cathepsin-L concentration is a marker of bone resorption, density
Medicure Inc. - Development program initiated for combined MC-1 and angiotensin receptor blocker
Meditech Research Limited - Collaborative research agreement to focus on hyaluronic acid based drugs
Medline Industries, Inc. - QuickSuite disposable operating room clean up system launched
Merck & Co. Inc. - A 7-deaza-adenosine analog strongly inhibits hepatitis C virus replication
Merck Research Laboratories - Degradation products of novel insulin sensitizer identified
Merck, KGaA - Early results show encouragement in treatment of glioblastoma brain tumors
Michigan Gastrointestinal Peptide Center - Ghrelin stimulates neurogenesis in the dorsal motor nucleus of the vagus
Michigan State University - IL-6 greater in preadipocytes than adipocytes of 3T3-L1 cells
Mini Mitter Co., Inc. - Telemetric core temperature monitoring system safe and effective
Mt Sinai School of Medicine, New York - Lasp-1 is a component of synapses and dendritic spines
NIR Diagnostics Inc. - Near-infrared instruments developer announced financial results
Nagoya National Hospital - Case of combined signet ring cell and glassy cell carcinoma reported
National Assoc. of Black Veterans, Region 1 - Washington State citizens' groups warn against Governor Locke's Rx Washington
National Cattlemen's Beef Association - Beef association comments on test results for bovine spongiform encephalopathy
National Human Genome Research Institute - Wnt gene signals show redundancy in modulating synovial joint formation
National Polytechnic Institute, IPN - Ether a go-go is a biomarker for human cervical cancer
National Sun Yat Sen University, Taiwan - CLBP and cardiotoxin genes diverged before appearance of numerous cardiotoxins
National Taiwan University Hospital - Phenytoin dosages for epilepsy correlate with CYP2C9/CYP2C19 polymorphisms
National University of Singapore - BMI may not be appropriate measure of obesity in Asian population
NeoPharm, Inc. - Tumor targeting compound clinical trial results presented at conference
New York University - Role of ascites-derived membrane vesicles in tumor growth studied
New York-Presbyterian Hospital - Utility of vagus nerve stimulation elucidated
North-West University - Using the glycemic index in meal-planning benefits diabetic patients
Northwestern University - Increased endocytotic pathway-mediated A beta 42 secretion in apoptosis
Noven Pharmaceuticals, Inc. - Pharmaceutical company announces addition to board of directors
Novogen Limited - Glycotex Inc. receives additional capital for development of Glucoprime
Nutrition - Strict diet can help fight diseases like Alzheimer, E.U. scientists say
Ohio State University - SMN2 gene copy number reveals the prognosis of spinal muscular atrophy
Oklahoma Medical Research Foundation - Choline deficiency induces time- and dose-dependent increase in ROS
Oregon State University - Dietary induction and inhibition of cytochrome P450s protein
Osaka University - Structure of erythrocyte NADH-cytochrome b5 reductase determined
PAREXEL International Corporation - Biopharmaceutical company partners with Korea Institute of Industrial Technology
PTS, Inc. - Glove Box maker appoints senior VP of international operations
Pain Medicine - Novartis withdraws application for E.U. approval of Prexige
Panacos Pharmaceuticals, Inc. - Proof-of-principle results for HIV drug candidate released
Patterson Companies, Inc. - Dental products value-added distributor announces improved financial results
PeaceHealth - University to examine physician training opportunities, staffing issues
Pharmacyclics, Inc. - Pharma company announces results from two clinical trials
Pharmaxis - Investigational New Drug application for Aridol filed with the U.S. FDA
Polytechnic University of Marche - Lack of in vitro protection by a common sunscreen ingredient reported
Protein Polymer Technologies, Inc. - Bioactive products producer reports third quarter 2004 financial results
Quality Medical Professionals - Medical staffing organization ready for holiday healthcare labor shortage
Quintiles Transnational Corp. - Pacific Biometrics and pharma services provider announce marketing partnership
Quixtar Inc. - New Trim Body System introduced to help support healthy weight loss
Roche - Study to examine efficacy of hepatitis C treatment in Latinos announced
Roche Pharmaceuticals - Biotech pharmaceutical firm gets U.S. FDA approval for lung cancer medicine
Royal Brompton Hospital, London - Corticosteroids are more effective than beta-agonists or leukotriene antagonists
Royal Free Hospital, London - Fusarium dimerum infection following SCT successfully treated with voriconazole
Royal Perth Hospital - Trial identified no benefit from lowering homocysteine with vitamin therapy
Rzeszow University of Technology - Mass transfer kinetics in chromatography of insulin variants determined
SRI/Surgical Express, Inc. - Surgical supply company names chief executive officer
Sahlgrens University Hospital, Gothenburg - Sox-2 expressed by neural progenitors and astroglia in adult brain
Sapir Medical Center, Kefar Sava - Fluorouracil induces apoptosis and surface molecule modulation of PBLs
Sapporo Medical University - Sodium channel subunit beta gene delivery complements anticancer therapy
Schepens Eye Research Institute - Study shows transplanted stem cells can prevent death of retina cells in mice
School Nutrition - Schools will reward kids who make good choices at lunch
Scientific American - New magazine exploring mysterious workings of the brain debuted
Semmelweis University of Medicine - Dystrophin expression mapped in rat brain
Sensitron, Inc. - Hospital CEO Lee Domanico joins wireless technology company's advisory board
Siemens Medical Solutions - Mobile C-arm with 3D imaging capabilities for OR use introduced
St. Louis University - African Americans receive less compensation for back injuries
Stanford University Medical Center - Young volunteers sought for study to test if infant rash cream prevents asthma
Starion Instruments - Medical instruments technology recognized by laparoendoscopic surgeons' group
State Univ. of New York at Albany - Blood lead concentration, dietary intakes studied in 3-12 month infants
Sterilox Technologies - Gregory T. Bosch elected president, CEO of medical disinfectants company
Sutura, Inc. - Medical device company signs merger agreement with Technology Visions Group
Target Stores - Retail chain offers gift card to benefit St. Jude Children's Research Hospital
Teranode Corporation - Life sciences software developer extends R&D platform through partnerships
The Henry J. Kaiser Foundation - Report examines benefit from Medicare prescription drug law
Tokai University - Non-viral gene transfer tracks gene expression in murine embryos
Tulane University - A mutation that causes exon skipping produces non-ocular Stickler syndrome
U.S. Agricultural Research Service - High fiber equals lower risks
U.S. Centers for Disease Control & Prevention - Vagococcus carniphilus isolated from ground beef
U.S. Centers for Disease Control & Prevention - Preventing infection among HIV+ men who have sex with men reviewed
U.S. Centers for Disease Control and Prevention - Egg quality assurance programs help reduce Salmonella Enteritidis illness
U.S. Centers for Disease Control and Prevention - Leukocyte antigen alleles linked to viral load in HIV seroconverters
U.S. Centers for Disease Control and Prevention - Rates of U.S. HIV/AIDS diagnoses are steady; racial disparities persist
U.S. Department of Agriculture - Study investigated mechanisms of vitamin E suppression of aortic lesions
U.S. Food & Drug Administration - Stability of St. John's Wort in aqueous solutions determined
U.S. Food and Drug Administration - FDA announces enhancement to isotretinoin risk management program
U.S. Food and Drug Administration - FDA proposes draft guidance for new plant varieties intended for food use
U.S. National Institutes of Health - Current approaches to increasing HDL involve infusions of apoA-I
U.S. National Institutes of Health - Exendin-4 pharmacodynamics conducted
U.S. National Institutes of Health - Frog metamorphosis characterizes the molecular dynamics of thyroid hormone
U.S.VA National Center for Patient Safety - U.S. VA patient safety division developing patient safety curriculum
UCLA Center for Health Policy Research - Report shows four million adults in California have high blood pressure
Umea University - Leptin effects on insulin secretion in isolated pancreatic islets studied
Univ. of California, San Diego - Regulated production of chemokine CCL28 in colon epithelium described
Univ. of California, San Francisco - Important priorities for prevention and treatment of HIV/AIDS
Univ. of Rovira & Virgili - Mannose-binding lectin gene polymorphisms are associated with GDM
Univ. of Texas Medical Branch - Mechanisms of action of the implantable gastric stimulator for obesity
University Hospital Schleswig Holstein, Germany - Study examined effects of mineralocorticoid receptors in response to stress
University Medical Center Utrecht - Effects of atorvastatin on fasting plasma, marginated apolipoproteins reported
University Roma La Sapienza - Autoimmune gastritis is an early event in juvenile patients with detectable PCA
University at Buffalo - Testosterone deficiency found in one-third of diabetic men
University of Alberta - Proinsulin secretion linked to graft function after islet transplant
University of Birmingham, U.K. - Disoriented T cells cause liver disease
University of Bristol - Copper impairs endothelium-dependent relaxation of aortae in diabetes
University of British Columbia - Type 1 diabetes progression linked to switch in CTL killing mechanism
University of California, Irvine - Pharmacological inhibition of ACAT ameliorates dyslipidemia
University of Cambridge - Neural contributions to motivational control of appetite in humans examined
University of Cologne - Scleroderma fibroblasts overexpress plasminogen activator inhibitor type 2
University of Colorado - Hepatopulmonary syndrome and portopulmonary hypertension reviewed
University of Dortmund - Nanoscopic gold spheres can be reversibly bound to DNA strands
University of Durban-Westville - Sclerocarya birrea extract is analgesic and anti-diabetic
University of Erlangen-Nurnberg - Feedback-based laser system shows promise for tissue-specific cutting
University of Ferrara - TRAIL blocks osteoclastic differentiation induced by RANKL + M-CSF
University of Florida - Genomic effects of Pseudomonas on CF cells determined
University of Florida - Piercings are a girl's best friend? Body art study shows gender preferences
University of Freiburg Hospital - Antibiotic use database used for benchmarking and resistance research
University of Geneva - DC-SIGN interference inhibits HIV transmission from dendritic to T cells
University of Georgia - The word mutation generates negative connotations in many people's minds
University of Glasgow - Clozapine enhances chronic PCP-induced regulation of prefrontal cortex receptors
University of Illinois - Integrin-mediated cellular functions selectively inactivated
University of Iowa - The brain renin-angiotensin system contributes to the pathophysiology of CHF
University of London - Peripheral tissues express transgenes after oral polyplex-based DNA vaccination
University of Massachusetts - Gateway-compatible yeast one-hybrid system developed
University of Milan - Characteristics of lean and obese women compared before and after menopause
University of Minnesota - Geographic distribution of resistant uropathogenic E. coli in U.S. outlined
University of Minnesota - Syndromic surveillance rapidly detects infectious disease outbreaks
University of New Mexico - Growth in human fibroblasts repressed by ionizing radiation
University of North Carolina - Atomic force microscopy identifies virus-specific interactions
University of North Texas - Novel CS1 splice variant identified in natural killer cells
University of Paris Sud - Reduced adverse effects seen with novel inhaled corticosteroid, ciclesonide
University of Parma - Activated NK/CD8+ cells express TRAIL and TRAIL receptors
University of Pennsylvania - Radiological features of treatment complications reviewed
University of Perugia - PAX5 is specific marker of B-cell ALL
University of Pittsburgh - HMG-CoA reductase is a target of agents that staunch angiogenesis
University of Queensland - Hepatic disposition kinetics of propranolol isomers characterized
University of Reims Champagne-Ardenne - G-quadruplex ligands may stop c-myc activity in tumor cells
University of Rochester - PGE2 inhibits chondrocyte differentiation through PKA and PKC signaling
University of Roma La Sapienza - Thyroid hormones regulate DNA-synthesis and cell-cycle proteins
University of Rome La Sapienza - Hypoglycemia increases uptake of glucose by retina
University of Shizuoka - Miniature on-line screening system for UGT inhibitors developed
University of Southern California - Pneumocystis pneumonia infection is a continuing public health issue
University of Sydney - Liver transplantation and changes in tacrolimus distribution studied
University of Toronto - Statin use reduces incidence of diabetes after renal transplantation
University of Toulouse - Hippocampal CA3-region is crucial for memory consolidation
University of Tsukuba - Nrf2 essential for efficacy of oltipraz against urinary bladder carcinogenesis
University of Tubingen - Apoptosis-inducing factor orthologue regulates apoptosis in yeast
University of Ulm - Genetic susceptibility in diabetes and thyroid disease reviewed
University of Virginia - Osteoblast adhesion to common biomaterials regulated through integrin binding
University of Washington - Metabolism of cyclosporine A by kidney CYP3A5 characterized
University of Wisconsin - Virtual colonoscopy can help patients avoid conventional procedure
University of Zagreb - Honey-bee products in cancer treatment and prevention
UnumProvident - Disability income insurer announces settlement of multistate market conduct exam
VTT Technical Research Center - International research team identifies gene that promotes prostate cancer
VU University Medical Center, Amsterdam - Tailored and targeted therapy possible in pediatric acute myeloid leukemia
Vancouver Hospital & Health Science Center - Allogeneic BMT increases long-term survival in advanced follicular lymphoma
Vanderbilt University, Nashville - Roles of prostaglandin receptors are determined by multiple factors
VaxGen, Inc. - Biopharm company enters agreement to raise $40 million through common stock sale
Verispan - Healthcare informatics company launches pharmaceutical data access sales system
Viragen, Inc. - Human alpha interferon for second-line therapy approved for sale in Bulgaria
Virginia Commonwealth University - Eliminating racial disparities would save more lives than technological advances
Virginia Commonwealth University - Ultrasound technique allowed real-time monitoring of total peripheral resistance
VisiJet Inc. - Opthalmic medical devices company reports third quarter 2004 financial results
VisiJet, Inc. - EpiLift system for corrective vision surgery introduced
Vital Images - Medical imaging software company files form 10-Q for 2004 third quarter
Washington University - Molecular partitioning during host cell penetration by Toxoplasma gondii
Washington University - Vaccine for food poisoning possible
Washington University, St. Louis - Nkx2-5 insufficiency perturbs the conduction system during development
Weizmann Institute of Science - Microarray analysis of IgG autoantibodies predicts diabetes in mice
Westmead Hospital - CD62L+ T cells less responsive to alloantigen stimulation than naive T cells
Yamanouchi Pharmaceutical Co., Ltd. - U.S. FDA approves Vesicare for the treatment of overactive bladder
Yamanouchi Pharmaceutical Co., Ltd. - U.S. FDA approves treatment for overactive bladder
Zambon Group - Pharmaceutical company withdraws from mono-ingredient inhalation project
Zhejiang University, Hangzhou - Biostability of collagen films controlled for fibroblast cytocompatibility
Zyomyx, Inc. - Founder Peter Wagner, PhD, named CEO of biotechnology company
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