Published in Pharma Investments, Ventures and Law Weekly, December 26th, 2004
"The matricellular protein CCN1 (CYR61) regulates multiple cellular processes and plays essential roles in embryonic vascular development," wrote S.J. Leu and colleagues, University Illinois.
"A ligand of several integrin receptors, CCN1 acts through integrin alpha(6)beta(1) and heparan sulfate proteoglycans (HSPGs) to promote specific functions in fibroblasts, smooth muscle cells, and endothelial cells.
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