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Pharma Investments, Ventures and Law Weekly

Susan Hasty, Publisher

Table of Contents . . . January 23rd, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pharma Investments, Ventures and Law Weekly | Other Publications

Abbott - Pharmaceutical firm announces 2005 sales, earnings guidance

Abgenix, Inc. - Biotech firm prices public offering of convertible senior notes

Aceto Corporation - Pharmaceuticals distributor reports 30% increase in stock dividend

Adeza Biomedical Corporation - Women's health product maker announces IPO

Animas Corp. - Cygnus inks $10 million asset-purchase agreement

Apotex, Inc. - $2M donated to faculty of pharmacy at University of Toronto

Array BioPharma, Inc. - Biopharmaceutical firm exercises over-allotment option, completes offering

Array BioPharma, Inc. - InterMune granted expanded rights under hepatitis agreement

Arryx, Inc. - Nano-device maker closes on $10M financing

Avitar, Inc. - Diagnostics company announces $1,285,000 private placement

BioForce Nanosciences, Inc. - Nanotechnology firm completes key funding round

Bioject Medical Technologies, Inc. - Drug delivery company receives milestone payment from Merial

Biomet, Inc. - Device firm reports 18% increase in net sales

Biopure Corporation - Pharmaceutical firm raises $11.6M through sale of common stock, warrants

Business and Finance - DrugMax, Inc., to be listed again under "DMAX" ticker symbol

Acacia Research Corp. - Amit Kumar appointed to board of the NanoBusiness Alliance

Agency for Healthcare Research and Quality - Young men, not teens, are least likely to use seat belts

Agriculture & Agri-Food Canada - A bovine genomic fragment shares some homology with epidermal growth factor

Aichi Human Service Center - Cleavage of calnexin caused by apoptotic stimuli clarified

Ajou University, Suwon - Effect of gender on early graft function depends on metabolic needs

Akdeniz University, Antalya - Levosimendan may best choice as a positive inotropic agent in clinical practice

Albert Einstein College of Medicine - Adipocyte differentiation changes NF-kappa B expression and activity

Alcon, Inc. - Retaane NDA submitted to U.S. and European regulatory authorities

Alexza Molecular Delivery Corp. - Daniel A. Spyker named VP clinical & regulatory affairs

Alliance Imaging, Inc. - Imaging services firm prices private offering of $150M of notes

Alpha-1 Foundation - NPS BioTherapeutics to continue Alpha-1 deficiency partnership

Alpharma, Inc. - Gabapentin tablets launched

Anadys Pharmaceuticals, Inc. - Positive data reported from phase II trial of ANA380

Angiotech Pharmaceuticals - Paclitaxel may benefit Alzheimer and Parkinson movement disorders

Aphton Corporation - Igeneon acquisition is a pivotal step in establishing oncology franchise

Applied NeuroSolutions, Inc. - Company to license technology to diagnose Alzheimer disease

ArTec, Inc. - Protocol for phase I (b) study of Tubercin completed

Ardent Pharmaceuticals, Inc. - Enhance Biotech announces closing of merger

Aristotelion University of Salonica - "Hour-glass" shape of uterus aids diagnosis of cervical pregnancy

Atactic Technologies - Inexpensive, mass-produced genes at core of synthetic biology advances

Avanir Pharmaceuticals - Approval of Neurodex sought for treatment of pseudobulbar affect

Barr Pharmaceuticals Inc. - U.S. FDA approves NDA for synthetic conjugated estrogen product

Bavarian Nordic A/S - Cancer vaccine developer establishes new operations in the U.S.

Becton, Dickinson and Co. - Collaboration to improve rapid tuberculosis diagnosis for HIV patients

Beijing Med-Pharm - Pharmaceutical distribution company acquired

Ben Gurion University of the Negev - Magnesium sulfate treatment for maternal hypoxia has pros and cons

Bentley Pharmaceuticals, Inc. - Pharmaceutical firm retains investor relations counsel

Berna Biotech Ltd. - Intranasal virosome influenza vaccine induces strong immunity in ferrets

Beth Israel Deaconess Medical Center, Boston - High risk score at presentation is associated with abnormal myocardial perfusion

Bio-Rad Laboratories, Inc. - Device firm prices private offering of $200M in notes

BioCrossroads - Biotech incubator names new president and CEO

BioMS Medical Corp - U.K. grants approval for pivotal multiple sclerosis trial

Biolase Technology, Inc. - New patent allowed for laser pulse technology

Biotech Holdings - Diabetes drug receives support from Mexican diabetes association

Bowling Green State University - Scarcity of HIV/AIDS risk-reduction materials targeting older adults

Brigham and Women's Hospital - Accumulated low-level lead exposure can lead to eye disease in men

Brigham and Women's Hospital - Role of cysteinyl leukotriene 2 receptor in murine inflammation clarified

Brown University - Children of migrant mothers less likely to receive all immunizations

CHU Lille - Long-term hearing thresholds determined in Vibrant Soundbridge users

CHU Montpellier - Serotonergic system genes implicated in vulnerability to suicidal behavior

CIGNA Behavioral Health - Committee for quality assurance awards behavioral health plan accreditation

CMS Media Affairs - Nursing home care improving in many areas Medicare center shows

Cancer Therapy - Study to gauge use of Ecstasy drug by terminal cancer patients

Catholic University of Korea - Inactivating mutations of Siah-1 may be factor in gastric cancer development

Cedars-Sinai Medical Center - Expression of chemokine receptor CXCR3 in IBD mucosa described

Cell Robotics International, Inc. - Medical device firm announces capitalization plan

Cephalon, Inc. - sNDA filed for new modafinil formulation for treatment of children and teens

Chembio Diagnostics, Inc. - Company completes trials for two HIV rapid tests; nears PMA submission

Cincinnati Children's Hospital - Study evaluates exercise-induced arm-leg gradient in CoA subjects

Cleveland Clinic Foundation - Expert calls for less direct-to-consumer advertising

ClinPhone - Clinical technology solution provider announces management additions

Coalition for Manitoba Pharmacy - Canada pharmacy group, seniors say U.S. report won't stop cross-border drugs

Complementary and Alternative Therapy - Some states have disciplined doctors for 'unorthodox' therapies

Copenhagen University - Antioxidants may not help fight cancer

Cornell University - Assay can be used to analyze or screen antioxidants against LDL oxidation

CryoLife, Inc. - Implantable tissue company files shelf registration statement

DATATRAK International, Inc. - ASP attains new internal records for global EDC implementations

Debiopharm, SA - Agreement inked for small-molecule MHC class II antagonists program

Del Laboratories, Inc. - Kelso to contribute additional funds to DLI Holding Corp.

DiscoveRx Corp. - Company introduces kinase assay portfolio

Domantis, Ltd. - AlbudAb technology launched to extend serum half-life of drugs

Drexel University, Philadelphia - Pindolol was equally effective for all categories of study subjects

Drug Treatment - Methamphetamine program to be offered in Billings

Duke University - Flow chamber studies may underestimate in vivo leukocyte adhesion

EKM Corp. - Electronic lab notebooks no longer part of the future

Eli Lilly and Company - Strattera label wears new safety warning

Eli Lily and Company - Leading pharmaceutical company increases dividends 38 years consecutively

ExonHit Therapeutics - Company achieves first research milestone in collaboration with Allergan

Eye Care Centers of America, Inc. - Investor, eye care centers advised by counsel to sell retail optical chain

FEI company - Company focused on electron beam technology announces board of directors

Federal University of Sao Paulo - Stunted children gain more fat mass than non-stunted children

Fitness & Wellness - Shrimp provide nutritional punch, American domestic shrimp industry group says

Fooyin University, Kaohsiung Hsien - Staurosporine induces G2 /M arrest in primary effusion lymphoma cells

Fresenius Medical Care, AG - Dialysis company awarded British Columbia Provincial contract

Fudan University - Matrix metalloproteinases are prognostic in patients with breast cancer

Fudan University - Plastic surface modification system enables on-chip enzyme microreactors

Fundacion Instituto de Inmunologia de Colombia -  Plasmodium vivax merozoite surface protein 8 characterized

Genmab A/S - Roche selects two antibiodies for clinical development

Genomic Health Inc. - New test can predict risk of breast cancer recurrence

GeoPharma, Inc. - Belcher parent retains The Anne McBride Co. as IR counsel

Georgetown University - Effects of dietary fat and NaCl on blood pressure examined

Georgetown University, Washington, DC - Women's satisfaction with BRCA1/2 genetic counseling varies

Ghent University Hospital - Vagus nerve stimulation safe and effective in long-term study

Gyeongsang National University - Fermented mushroom milk improved hyperlipidemia in diabetic rats

Harbor-UCLA Medical Center, Torrance - Novel luciferase-like protein identified in human female reproductive tract

Harvard University - Dendritic cells fused with human cancer cells described

Harvard University - Distinct HIV-1 subtype A3 circulating in West Africa

Harvard University - T-cell receptor tetramers bind MHC-peptide complexes with high affinity

Harvard University - U.S. FDA okays Ecstasy study in cancer patients

Health Industries Research Cos. - Report: Pfizer is industry leader in account management

Henry Ford Medical Center - Novel robotic system facilitates urologic microsurgery

Hohenheim University - Differentiated CACO-2 cells modulate cytokine release

Hollis-Eden Pharmaceuticals, Inc. - Update provided on Neumune development program in acute radiation syndrome

Hoshi University - Mechanism of contractile response to endothelin in diabetic artery reported

Hospital Council of Western Pennsylvania - Western Pennsylvania year-end hospital financial report released

Influenza Vaccines - Wisconsin lifts flu shot restrictions

Innogenetics - Milestone achieved in development of rapid molecular microbiology testing assay

Institute Luois Malarde, Tahiti - Genome from severe 2001 dengue-1 epidemic in French Polynesia characterized

Institute Pasteur, Paris - HIV-1 triggers mitochondrion death

IntegraGen - DNA chips to become 'identity cards' for cancer tumors

Intracorp - Comprehensive medical provider network solution offered to California companies

Iowa State University - Stability of variables linked to metabolic syndrome outlined

Istituti Ortopedici Rizzoli, Bologna - Genetic profile determined through chromosome CGH and DNA microarrays

Istituto Superiore di Sanita - Changes in hemagglutinins and neuraminidases of influenza B viruses outlined

Italian National Research Center on Aging - Polymorphism affects PAI-1 response to vitamin E in type 2 diabetic patients

Izalex, Inc. - Speier to use medical device development experience in role as vice president

Karolinska Institute - ALK7 is not essential mediator of Nodal signaling during mesendoderm formation

Karolinska Institute - Glucagon-like peptide-1 on benefits diabetic patients with stable CAD

Kimron Veterinary Institute - Small interfering RNA inhibit foot-and-mouth disease virus replication

Konkuk University, Seoul - Korean New Castle disease virus isolates sequenced and phylogenetically analyzed

Kyoto Prefectural University of Medicine - Villus epithelial injury from nematode linked to granzyme B upregulation

Kyushu University Hospital, Fukuoka - Case reported of inhibin-producing granulosa cell tumor causing amenorrhea

LabOne, Inc. - Diagnostic services provider announces earnings guidance for 2005

Launch Into Learning - Multimedia product for children with autism launched

Los Angeles Biomedical Research Institute - WHI data provide impetus for evaluating insulin level change and cancer risk

Lumenis Ltd. - Light based medical technology company appoints board member

MannKind Corporation - Pharma company releases trial data for Technosphere Insulin

Massachusetts General Hospital - Two atypical antipsychotics may be associated with increased risk of diabetes

Massachusetts General Hospital, Boston - Attitudes of physicians and consumers differ about prescription medications

Matria Healthcare - Disease management announces outlook for 2005

Max Planck Institute - Probabilistic model demonstrates ability to forecast spread of epidemics

Mayo Clinic & Mayo Foundation - Mitochondrial regulation of apoptosis affects HIV pathogenesis and treatment

McGill University - Bleomycin-induced pulmonary fibrosis studied, protein changes revealed

McGill University - Cyst wall protein in Giardia trophozoites and embryonic kidney cells is similar

MedImpact Healthcare Systems, Inc. - Pharmacy benefit management company joins health transformation organization

Medivation, Inc. - Medical technologies company announce merger

Mental Healthcare - Michigan Governor signs bill requiring outpatient treatment for mentally ill

Mentholatum company, Inc. - Health care products manufacturer acquires OXY brand

Mercy Hospital, Auckland - Report clarifies deployment strategies for the crush stent technique

MidMichigan Health - Gratiot Health System announces full affiliation with healthcare organization

Moliris, Inc. - Pharma company focuses development on treatment of antibiotic-resistant Staph

MorphoSys AG - Pharma company receives approval for phase 1 trial of anticancer antibody

Mostoles General Hospital - Neurosyphilis can masquerade as corticobasal ganglionic degeneration

Mount Sinai School of Medicine - Cidofovir in papillomatosis minimizes need for repeated surgical excision

Myogen, Inc. - Biopharmaceutical company appoints vice president

NMT Medical, Inc. - Medical device company announces stock sale

National Hemophilia Foundation - Hemophilia foundation board names new CEO

National Institute of Animal Health, Ibaraki - Nipah virus-specific monoclonal antibodies identified

National Institute of Cardiology, Mexico City - Alternative oxidase activity is part of cellular response to oxidative stress

National Taiwan University - Radical hysterectomy may exacerbate pre-existing abnormal urodynamics

National Taiwan University, Taipei - Mosquitoes contribute to evolutionary conservation of dengue virus

National Yang Ming University, Taipei - Study sheds light on maternal role transition in PROM cases

Natl. Institute of Agronomic Research, Nouzilly - Train A protein secreted and reabsorbed by same epididymal cells

NeighborCare - Institutional pharmacy provider completes merger of Belville Pharmacy

NeoPharm, Inc. - Pharma companies partner on Cationic Cardiolipin-based NeoPhectin technology

Neoprobe Corporation - Surgical technology company announces issuance of financing

Netherlands Institute for Development Biology - Transcriptional activity of Smad proteins in development monitored in vivo

New York United Hospital Medical Center - New York hospital files for bankruptcy

Nippon Dent. University of Tokyo - Structure of a cytolethal distending toxin elucidated

North Dakota State University - Depth perception and drunk driving

Northwestern University - Interstitial flow controls lymphatic and blood endothelial cells differentially

Norwegian Radium Hospital, Oslo - BRCA1 mutation prevalence in ovarian tumors is low in Norway

Nutrition - Nutritionist offers advice for staying healthy in 2005

Nutritional Supplements - Proliferation of health information makes vitamin aisle confusing

Oakland University - Passive stiffness of rat sperm determined

Oncolytics Biotech Inc. - Biotech company announces proceeds of private placement

PDI, Inc. - Outsourced sales and marketing services company announces financial estimates

Pan American Health Organization - Vaccine contributions to health highlighted at expert meeting

Park-Klinik Weissensee, Berlin - Debunking constipation myths: the truth about high-fiber diets and laxatives

Partners Telemedicine - Wounds can be successfully monitored remotely, according to study

Penn Pharmaceutical Services - Pharma firm names three management appointments

PharmaBio Development - Cell Therapeutics inks TRISENOX financing agreement

Proteome Systems - Eukarion acquisition agreement signed

Providence VA Medical Center - Basis of pulmonary endothelium barrier dysfunction and RhoA activation revealed

Q Mark, Inc. - Management software company and Diversified Data Design announce alliance

Radiation Effects Research Foundation, Hiroshima - C-reactive protein levels are influenced polymorphism of LT Alpha

Response Biomedical Corp. - Biomedical company announces agreement with Haywood Securities

Roche Pharmaceuticals - PEGASYS approved for chronic hepatitis B in Switzerland

Rovira i Virgili University - Humans exposed to polybrominated diphenyl ethers through diet

Royal Brompton Hospital, London - Cachexia develops in malaria similarly to cachexia of chronic heart failure

Royal Children's Hospital, Parkville - People working in public health and genetics need to collaborate

Royal Perth Hospital - Uncoupling proteins have potential role in HIV lipodystrophy

Rush University Medical Center - Foundation gives medical center $7.5 million contribution for emergency response

Russian Academy of Science -  E. magnusii mitochondria lack a functional Ca2+-dependent pore

SCOLR Pharma, Inc. - Pharma company announces amino acid patent filing

SMV Center for Biotechnology, India - Herbs attenuate stress-mediated cell injury during oxygen-glucose deprivation

Schering-Plough Corporation - Pharma company appoints vice president of global communications

Scripps Research Institute - Central amygdala GABA release elevated in ethanol-dependent rats

Seoul National University - Premenopausal status and combined effect of three genotypes increases risk

Shriners Hospital for Children, Boston - Tissue engineered liver support systems not reliable for routine clinical use

South Medical Hospital and Clinical Foundation - Triple combination therapy succeeds in chronic hepatitis C non-responders

Spedali Civil Brescia - Terminal ureterectomy with ureterocystoneostomy effective for ureteral blockage

St. Jude Medical, Inc. - Medical device company announces completion of surgical cardiac ablation case

State University of New York, Buffalo - Hypogonadotropic hypogonadism is common in patients with type 2 diabetes

Substance Abuse - Treatment a cost-effective way for Kentucky to help methamphetamine abusers

Surgical Information Systems - Automating anesthesia emerging as top priority for U.S. hospitals

Swiss Federal Institute of Technology, Ruschlikon - Thyroid function studied, deficiency and excess vitamin A influences revealed

TLC Vision Corporation - Eye care services company announces stock buy-back program

Taichung Vet. General Hospital - Anterior colporrhaphy may adversely effect urethral sphincter function

Takeda Europe R&D Center - Cardiovascular effects of oral therapies for type 2 diabetes vary

Technion-Israel Institute of Technology - New gel supports and regenerates broken bones

Teva Pharmaceutical Industries Ltd. - Pharmaceutical company gets tentative approval of generic type 2 diabetes drug

The College Network - Educational publisher announces alliance with National League for Nursing

The Cranberry Institute - Ingredient in cranberries provide key anticancer compound

The Quantum Group, Inc. - Healthcare services provider completes acquisition of software platform

TheraSTrat - Theragenomics knowledge management and discovery software for ADRs released

Therion Biologics Corporation - Phase I study for antitumor CEA-TRICOM published

Tufts Health Plan - Health plan provider, CIGNA HealthCare form strategic alliance for national plan

U.S. Army Research Institute of Infectious Disease - Potential of variola infection of macaques as smallpox model investigated

U.S. Department of Agriculture - Low pathogenic AI virus/ND virus inactivated in egg products via pasteurization

U.S. Department of Veterans Affairs - U.S. veterans get top care from VA, study by RAND researchers finds

U.S. Food and Drug Administration - FDA recordkeeping rule to enhance the security of the U.S. food supply

U.S. National Institutes of HEalth - Normal growth, development, and life span does not involve carbonic anhydrase

U.S. National Institutes of Health - Modified vaccinia virus vaccine protects against lethal challenge

U.S. National Institutes of Health - NC function in MLV budding/infectivity distinct from viral late-domain function

U.S. National Institutes of Health - Novel tetrameric analog of indolicidin potent inhibitor of HIV-1 integrase

Univ. of California, Irvine - Resiquimod is new vaccine adjuvant for Th1 immune responses

Univ. of California, San Diego - Immune system contributes to evolution of a new fluorescent protein

Univ. of California, San Francsico - Costs higher for children with special healthcare needs

Univ. of Washington, Seattle - Social development program in childhood aids in positive functioning as an adult

Universidade Estadual do Centro Oeste-Unicentro - Rhoptries from Toxoplasma gondii tachyzoites isolated

Universite Francois Rabelais - Methods to improve rituximab efficacy reviewed

University Clinic, Aachen - Technique provides prognostic data in patients undergoing revascularization

University of Alberta - Drug may hinder recovery from heart attacks

University of Arkansas Med Science - Researchers report on case of localized diffuse giant inflammatory polyposis

University of Athens - Quantity of collagen type I and III mRNA less in women with SUI

University of Bristol - Parenteral influenza vaccine influences T cell-mediated immunity in adults

University of California Berkeley - Vertebrate odorant receptor analyzed, ligand selectivity determined

University of California Los Angeles - Cryoelectron microscopy imaging of vaults localizes two proteins

University of California San Francisco - Researchers address key issues in hepatocellular carcinoma management

University of Cambridge - Both immunological, neurobiological functions contribute to tissue injury

University of Chicago - Evidence suggests human brain evolution was a special event

University of Cologne - Review describes the basic mechanisms controlling mitochondrial biogenesis

University of Copenhagen - Angiopoietin-2 breaks the angiogenic synergy of major cytokines

University of Copenhagen - Factors influencing gestation length and birth weight in Zimbabwe studied

University of Edinburgh - Scientists study fish oil diet in bid to cut heart attack risks

University of Florida - Activity of alamin adenosyltransferase clarified

University of Florida - Peanuts rival fruit as source of health-promoting antioxidants

University of Guelph - Fatty acids and exercise affect glucose transport but not tumor growth

University of Halle Wittenberg, Halle Saale - Natriuretic peptides may have a role in monitoring therapy success

University of Illes Balears, Palma de Mallorca - Dot-blot EIA rapidly detects RSV antigen from pediatric nasopharyngeal aspirates

University of Leicester - Endocannabinoid N-arachidonoylethanolamine has role in normal labor

University of Maryland, Baltimore - Consolidation chemotherapy for relapsed/refractory Hodgkin disease feasible

University of Michigan - Study investigates value of "center of excellence" designation

University of Modena & Reggio Emilia, Modena - Novel approach analyzes mitochondrial toxicity induced by NRTIs

University of Nebraska - Phosphorylation regulates cell growth and kinase stability and activation

University of Nebraska - Regulation of BCL2 protein expression in B cells clarified

University of Newcastle Upon Tyne - Cardiac complications are a primary part specific limb-girdle muscular dystrophy

University of North Carolina - Growth of vascular smooth muscle studied, transactivation of receptor involved

University of Otago, Dunedin - Neurointermediate lobe of pituitary has regulatory role in prolactin secretion

University of Pittsburgh - Hostility, distraction affect women's CV recovery from anger recall differently

University of South Carolina -  Amphitrite ornate dehaloperoxidase studied, enhanced activity revealed

University of South Paris - Myocardial injury could be caused by enhanced effects of isoproterenol by TNFa

University of Tennessee - Coordinated RhoA and Rac1 is needed for bronchial epithelial wound repair

University of Texas, Dallas - Punctate exanthema common cutaneous presentation in West Nile Virus infection

University of Texas, San Antonio - Use of wavelet regressions hastens normalization of cDNA microarray data

University of Thessly - Enteroviruses responsible for outbreak of aseptic meningitis identified

University of Tokyo - Functional roles of kinesin superfamily proteins

University of Toronto - Emergency outbreak planning lacking in Canada during 2003 SARS outbreak

University of Utah - Dye reversal microarrays used to identify cytogenetic abnormalities

University of Utah - Protein release from multiblock copolymer-based microspheres characterized

University of Vienna - Culture-expanded autogenous bone cells can improve bone formation

University of Virginia - MDCT angiography can highlight patients who are at greater risk of stroke

University of Wageningen & Research Center - Real-time PCR quickly/accurately detects S. enterica and E. coli O157:H7

University of Washington - Oral estradiol dose for postmenopausal women with CKD should be cut 50% or more

V-Net Beverage, Inc. - Beverage company and laboratory partner to develop Allicin sublingual spray

Ventas, Inc. - Healthcare real estate trust sells two hospitals to tenant, Kindred Healthcare

VizX Labs - GeneSifter Data Center launched

Washington University - Cobalt wire-based rat model of focal epilepsy constructed

Washington University, St. Louis - Older women less likely to receive most aggressive treatments

Washington University, St. Louis - SC expression of AML1/ETO fusion protein induces myeloproliferative disorder

WellCare Health Plans, Inc. - Company receives CMS approval to offer managed care coverage to Medicare users

Wyeth Research - LDL could promote vascular liberation of arachidonic acid

Xinqiao Hospital, Chongqing - SVZa neural stem cells differentiate into distinct lineages in response to BMP4

Xtria, LLC - IT company signs 3-year agreement with Texas medical center for imaging services

Yonsei University, Korea - Job characteristics were not associated with cardiovascular risk factors

Yonsei University, Seoul - Epidural analgesia reduces pain scores more than IV fentanyl analgesia

Zentaris GmbH - Pharmaceutical company receives approval to market leishmaniasis drug in Germany

Zhengzhou University - Findings support role of genistein in colon tumor prevention, growth reduction

Zimmer Holdings - Holdings company announces MIS agreement with U of Nebraska Medical Center

Zoe Medical - Delphi Medical licenses vital signs monitoring technology

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