University of Tokyo
DRG regulatory proteins identified, specific regulation revealed
Published in Pharma Investments, Ventures and Law Weekly, April 10th, 2005
"DRG1 and DRG2 comprise a highly conserved subfamily of GTP-binding proteins and are thought to act as critical regulators of cell growth. Their abnormal expressions may trigger cell transformation or cell cycle arrest. Our aim is to clarify their physiological functions and regulatory mechanisms," wrote K. Ishikawa and colleagues, University of Tokyo.
"Here we report identification of novel proteins, DFRP 1 and DFRP2, which regulate expression of DRG proteins through specific binding. In transient...
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