Published in Pharma Investments, Ventures and Law Weekly, August 7th, 2005
"Numerous protein kinases have been implicated in visual cortex plasticity, but the role of serine/threonine protein phosphatases has not yet been established. Calcineurin, the only known Ca2+/calmodulin-activated protein phosphatase in the brain, has been identified as a molecular constraint on synaptic plasticity in the hippocampus and on memory," wrote Y. Yang and colleagues, Yale University.
"Using transgenic mice overexpressing calcineurin inducibly in forebrain neurons, we now provide...
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