Kumamoto University
Glycyrrhizin with capric acid has synergistic absorption-enhancing effect
Published in Pharma Investments, Ventures and Law Weekly, September 18th, 2005
In a recent study from Japan, the "absorption-enhancing effect of the simultaneous administration of sodium caprate (Cap-Na) and dipotassium glycyrrhizinate (Grz-K) was investigated to clarify an effect of Grz-K."
"A combination of 0.1% (w/v) Cap-Na and 2% (w/v) Grz-K had a rapid and long-lasting absorption-enhancing activity in Caco-2 cell monolayers under conditions where Cap-Na and Grz-K showed a weak and no activity, respectively," T. Imai and coauthors at Kumamoto University found.
"The simultaneous treatment of a Caco-2 cell monolayer...
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