Otto Von Guericke University, Magdeburg
Cytosolic adaptor protein required for proper activation of immune system
Published in Pharma Investments, Ventures and Law Weekly, November 6th, 2005
According to recent research published in the journal Molecular and Cellular Biology, "SKAP-HOM is a cytosolic adaptor protein representing a specific substrate for the Src family protein tyrosine kinase Fyn. Previously, several groups have provided experimental evidence that SKAP-HOM (most likely in cooperation with the cytosolic adaptor protein ADAP) is involved in regulating leukocyte adhesion."
M. Togni and associates reported, "To further assess the physiological role of SKAP-HOM, we investigated the immune system of SKAP-HOM-deficient mice. Our data...
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