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University of Wisconsin

Flu virus reported to resist drug envisioned for pandemic

Published in Pharma Investments, Ventures and Law Weekly, November 6th, 2005

An avian influenza virus isolated from an infected Vietnamese girl has been determined to be resistant to the drug oseltamivir, the compound better known by its trade name Tamiflu, and the drug officials hope will serve as the front line of defense for a feared influenza pandemic.

Scientists from the University of Wisconsin-Madison, working with colleagues in Vietnam and Japan, report in a brief communication in the October 20 edition of the journal Nature that a young girl, provided with a prophylactic dose of the drug after experiencing mild influenza symptoms, developed a strain of the virus that was highly resistant to the drug.

The...

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