Pharma Investments, Ventures and Law Weekly

Niigata University - Risk of neck cellulitis should be monitored for 1 year after neck dissection

North-West University, Potchefstroom - Consumption of nuts may significantly decrease cholesterol

Nova Southeastern University, Ft. Lauderdale - Florida groups get $4.2 million grant from U.S. HRSA for disaster preparedness

Novartis Institute of Medical Science - Calcitonin gene-related peptide and TRPV1 may contribute to osteoarthritis pain

OCG Technology, Inc. - PrimeCare Systems awards license to Argentina-based Telemedica

Ohio University - Chagasic serum inhibits Trypanosoma cruzi egress from tissue culture cells

Okayama University - Epigenetic change of sex chromosomes linked to tumorigenesis of ameloblastoma

Ophthonix - Vision technology company secures $17 million

Ortek Therapeutics, Inc. - Toothpaste study: Experimental cavity fighting complex more effective than fluoride

Osaka University - Donor leukocyte infusion may be a potential treatment for cytomegalovirus retinitis

Oxford University - Deep brain stimulation can lower blood pressure

Pamela Youde Nethersole Eastern Hospital - Non-invasive ventilation for respiratory failure lowers intubation and death rates

Peking University, Beijing - Expansion capacity of mesenchymal stem cells after sex-mismatched SCT is damaged

Polytechnic University of the Marche Region Medical School, Ancona - Vascular endothelial growth factor differentiates clear cell renal carcinomas

Primagen Holding B.V. - Molecular tests company investigating collaboration for testing blood samples

Pusan National University - Costunolide inhibited telomerase activity in human breast carcinoma cells

Rambam Medical Center, Haifa - ACE isoform shift may contribute to cardiac remodeling in response to hemodynamic overload

Reata Pharmaceuticals, Inc. - Clinical testing approved for therapy of relapsed and refractory leukemias

Recom Managed Systems - Life sciences company appoints Keitt and Sosebee to cardiac services division

Robert Jones & Agnes Hunt Orthopedic Hospital, Oswestry - Outcome of giant lipomatous tumors of hand and forearm discussed

Roche - Partnership to develop prototype system for psychotropic drug therapies

Roswell Park Cancer Institute, Buffalo - Genetic aberrations may be possible molecular fingerprint of radiation-associated breast cancer

Royal Marsden Hospital, London - Neoadjuvant vinorelbine/epirubicin compared well with adriamycin/cyclophosphamide

Salzburg University - Novel protocol improves consistency and reduces morbidity

Savient Pharmaceuticals, Inc. - Pharma company appoints Gina Gutzeit interim chief financial officer

Schering AG - European Commission approves magnetic resonance angiography contrast agent

Seattle Biomedical Research Institute -  Haemophilus influenzae homologue of luxS modulates biofilm virulence

Seoul National University - Oral alendronate safe and effective for pediatric treatment

Sheba Medical Center, Tel Aviv - Cardiac valve pathology may be risk factor for several types of CNS involvement

Silverlink Communications - Voice automated software developer announces Medicare Part D suite

Sorin Group - New generation cardiac resynchronization therapy products introduced at meeting

Specialty Laboratories, Inc. - Reference lab, Roche Diagnostics signs agreement to offer assay for genetic testing

Spectrum Pharmaceuticals, Inc. - Cancer-focused pharmaceutical company expands scientific advisory board

St. Jude Medical, Inc. - New device closes heart defect, preventing unfiltered blood from entering circulation

St. Luke's Episcopal Hospital, Houston - Pravastatin therapy offers long-term benefits to heart transplant recipients

St. Orsola Marcello Malpighi Hospital, Bologna - Use of F-18-FDG PET/CT aids in evaluation of recurrent ovarian cancer

St. Vincent's Hospital, Darlinghurst - CCR5+CD4+ cells highly activated during primary HIV-1 infection

Stanford University - DDAH-I overexpression attenuated graft coronary artery disease

State University of New York - Increased television watching plays a part in childhood obesity?

Statens Serum Institute, Copenhagen - Cancer susceptibility in nasopharyngeal carcinoma families described

Stoltenberg Consulting Inc. - Healthcare IT consulting firm, mobile devices maker partner to integrate systems

Sungkyunkwan University, Seoul - Review of multiphasic helical and previous serial CT images recommended

Surface Logix Inc. - Phase 1 trial of inhibitor to treat endothelial dysfunction achieves target profile

Taipei Medical University - Automaticity was more easily induced by Ba²⁺ in pulmonary veins than in left atria

Taiwan National University - Multiple myeloma cytogenetic abnormalities in Asia compared with those documented in the West

Tampere University Hospital - Paracervical block and OB experience play important role in labor pain relief

Tokyo University of Agriculture & Technology - Alpha-synuclein double mutant prevents fibril formation

Topigen Pharmaceuticals Inc. - Respiratory-focused biopharm company adds CDN$6 million investment from Quebec firm

Toronto General Hospital - High C2 levels associated with fewer episodes of cellular rejection after heart transplantation

Toronto General Hospital - Nocturnal hemodialysis is associated with restoration of EPC biology in ESRD

TorreyPines Therapeutics, Inc. - New alliance signed regarding genetic research program for Alzheimer disease

Trudeau Institute Inc. - Aging reduces immune memory

Turku University Hospital - Investigators explored association of sex hormones with risk of ovarian cancer

U.S. Centers for Disease Control & Prevention - Method to measure perfluorinated organic acids and amides in serum developed

U.S. Military HIV Research Program - In-depth analysis of heterosexual HIV-1 superinfection reported

U.S. National Cancer Institute - Diet with tocopherols raises GCC risk; fruits, vitamin C, tocopherols, and lycopene cut GNCC risk

U.S. National Cancer Institute - Polymorphisms in folate metabolic genes linked to lung cancer risk in Xuan Wei, China

U.S. National Institute of Allergy & Infectious Diseases - Immune complex detection does not confirm active infection with B. burgdorferi

U.S. National Institute of Child Health & Human Development - Planned caesarian section is safe and effective for preventing transmission of HIV

U.S. National Institute of Child Health & Human Development - VDAC review highlights important controversial roles of VDAC in mitochondrial function

U.S. National Institutes of Health - Aminoterminal domains work with alternatively spliced hexapeptide, makes MITF antiproliferative

U.S. National Institutes of Health - Human parainfluenza virus type 1 vaccine candidate is attenuated and effective

Uniformed Service University of Health Science, Bethesda - Endogenous neuregulin restores radial glia in a model of cortical dysplasia

Universidade Federal do Rio de Janeiro - Arginine methyltransferase PRMT1 homologue from Schistosoma cloned

Universita' di Tor Vergata, Rome - Cellular genetic therapy reviewed

University Clinic, Dusseldorf - Glucose deprivation preconditions isolated rat hearts

University Hospital of Salzburg - Higher cycle of epidoxorubicin/docetaxel increased pathological response rates

University Vita e Salute San Raffaele Hospital, Milan - Circulating ouabain and BP are increased in offspring of hypertensive families

University of Alabama - Intestinal helminth treatment does not reduce plasma HIV-1 RNA in coinfected patients

University of Athens - Imiquimod cream may be viable alternative treatment for HPV-positive women

University of Athens - Myocardial contrast echocardiography detects changes developing in coronary microcirculation

University of Basel Hospital - Early stem cell transplantation induced remission of chronic myeloid leukemia

University of Buenos Aires - Antibodies against T. cruzi ribosomal protein form pattern of epitope recognition

University of Calabria, Rende -  Achillea ligustica extracts possess antidiabetic activities

University of Calgary - Quorum-sensing mutations affect B. cenocepacia biofilm attachment and stability

University of California, Berkeley - Sequence and size of non-polar residues affect self-assembly of amphiphilic peptides

University of California, Davis - Guidelines devised for surgical palliative care of patients with urological malignancies

University of California, Los Angeles - Implant-based facial prosthesis has higher user ratings than adhesive-based prosthesis

University of California, San Francisco - Different mechanisms of ventricular fibrillation may be present in LV

University of California, San Francisco - Insurance company rewards to doctors and hospitals may not improve care

University of Cologne - Doctors can halve the radiation dose and still retain high survival in Hodgkin lymphoma

University of Connecticut - Article summarizes effects of fatty acids on plasma lipid concentrations

University of Copenhagen - Mechanism of natural immunity to malaria may aid vaccine development

University of Dundee - Developing fetus expresses more detoxification enzyme sulfotransferase than adult

University of Edinburgh - SJG-136 shows antitumor activity against A2780 xenografts but not A2780(AD) xenografts

University of Erlangen-Nurnberg - Phototherapeutic keratectomy has poor long-term outcome

University of Frankfurt Klinikum - Valproic acid stimulates CMV replication in retinal pigment epithelial cells

University of Geneva - Transcription factor selectively increases ion permeability and modulates tight junction proteins

University of Georgia - U.S. CDC grant to fund center to focus on health of the poor

University of Halle Wittenberg, Saale - Betulinic acid induces apoptosis in skin cancer cells

University of Heidelberg Eye Hospital - Novel foldable monofocal intraocular lens has 1 CU accommodative power

University of Helsinki - Matrix metalloproteinase-3 and interleukin-1 beta are important in rheumatoid arthritis

University of Hong Kong - FTY720 arrests tumor and neovascular growth in liver cancer models

University of Hong Kong - Patients with untreated hepatocellular carcinoma face grim outcomes despite supportive treatment

University of Illinois - Distinct cytokine patterns exist in peripheral blood mononuclear cell cultures

University of Istanbul - EIA accurately diagnoses H. pylori in stool of dyspeptic patients after eradication therapy

University of Kentucky - Kentucky College of Pharmacy to develop treatments for people after radiation exposure

University of Leuven - Sr-90 brachytherapy recommended for small- to medium-sized uveal melanoma

University of Maryland - T cell adaptor protein is recognized by a domain of phospholipase C

University of Milan - Fibromyalgia patients have enhanced CV sympathetic activity while recumbent

University of Milan - Retrotip type, tooth type/location, and post restoration don't affect outcome

University of Missouri - H₂ O₂ activation of p38 MAPK pathway shown to properties in astrocytes

University of Nebraska - Contrast echo has high diagnostic accuracy for detecting coronary artery disease

University of North Carolina - HIV-1 RNA and CD4 count moderately but inconsistently associated with malaria parasitemia

University of North Carolina - Mucin granules closely contact tubular elements of the endoplasmic reticulum

University of Oklahoma - HDL levels decrease early in life in Cherokee Indian children

University of Pennsylvania - Inhibition of activated K-Ras promotes radiation killing of pancreatic carcinoma

University of Pittsburgh - Extracellular matrix scaffold and muscle tissue used to reconstruct esophagus

University of Pittsburgh - Genomic instability may be hereditarily different, resulting in different molecular pathogenesis

University of Queensland - Climate dependent variations in fly abundance may contribute to transmission of RHDV

University of Regensburg - Temporary cements do not affect bond strength of ceramic luted to dentin

University of Texas Health Science Center, San Antonio - Heat shock response protects murine liver from endotoxemia-induced injury

University of Texas SW Medical Center, Dallas - Tuberculosis poses a risk to a pregnant woman and her fetus

University of Texas School of Public Health, Houston - Biology, epidemiology, and prevention of HPV infection are reviewed

University of Toronto - Neural stem cells partition DNA asymmetrically

University of Toronto - Therapeutic use for umbilical cord blood may broaden

University of Utrecht - Patient factors associated with delay in primary care of head and neck carcinoma

University of Washington - Interferons act to allow clonal expansion in response to viral infection

University of Washington - Suprabasal keratinocytes participate in wound reepithelialization

University of Washington - Widespread protein insolubility detected early in Alzheimer disease

University of Western Ontario - Gap between biomedicine and psychosocial reality risks patients' emotional well-being

University of Wisconsin - Protein-acrylamide copolymer hydrogels quantitatively determine tyrosine kinase activity

University of Wisconsin-Parkside -  Pasteurella multocida may naturally associate with free-living amoebae

University of Wurzburg - Dynamic differences may contribute to electrical instability in diseased hearts

University of the West Indies - Mental stimulation through play has an effect on children with stunted growth

Vanderbilt University, Nashville - Prostaglandin D₂ contains an eicosanoid-binding chemoattractant receptor

Vanderbilt University, Nashville - Study maintains soy food consumption may reduce risk of fracture

Varian Medical Systems - Radiotherapy equipment contract extended for 7 years at U.K. oncology center

Ventracor Limited - Exchange of ventricular assist system controllers complete, company reports

Vertex Pharmaceuticals Incorporated - Biotech company to focus on developing hepatitis C, arthritis, CF drugs

Virginia Commonwealth University - U.S. NIH awards $3.7M grant for development of molecular imaging, brain tumor therapy agent

Viventia Biotech Inc. - Health Canada grants clearance to initiate phase 2 cancer trial for Proxinium

Vrije University of Amsterdam - Feeding route of Glu does not influence renal Arg synthesis

WEX Pharmaceuticals Inc. - Preliminary results of phase 2a trial of drug for severe cancer-related pain reported

Wake Forest University, Winston-Salem - Steroids treatment may result in more severe chickenpox

White Mountain Capital, LLC - Analyst reiterates buy rating on Nabi Biopharmaceuticals before clinical trial data release

Wright Medical Group, Inc. - Orthopedic medical device company reports net sales for Q3 2005 of $73.4 million

YM BioSciences Inc. - Report suggests new regimen for prostate cancer treatment more effective

Yale University - Research on premature birth boosted with $10 million U.S. NIH grant

Yeungnam University, Kyongsan - Interleukin-4 is essential for the expression of Ym1/2 genes

Yonsei University, Seoul - Soft-tissue axillary masses profiled by sonographic appearances

Zhejiang University, Hangzhou - Nitric oxide inhalation inhibits inducible nitric oxide synthase in meconium-induced lung injury

ev3 Inc. - Endovascular device company reports Q3 2005 net sales up 70% to $33.5 million