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Panjab University, Chandigarh

Resveratrol, a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats

Published in Pharma Investments, Ventures and Law Weekly, March 5th, 2006

Resveratrol, a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats.

"Diabetic nephropathy is a serious microvascular complication and one of the main causes of end-stage renal disease. Various studies have revealed that increased oxidative stress is a major pathophysiological mechanism which is involved in the etiology of diabetic nephropathy," scientists writing in the journal Pharmacology report.

S. Sharma and colleagues at Panjab University explained, "Resveratrol, a polyphenolic phytoalexin present in red wine, is known to possess potent antioxidant properties and thus we aimed to examine its effect on renal function and...

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