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University of Toronto

Researchers from Canada, Sweden and the United States report details of new studies and findings in the area of cardiology

Published in Pharma Investments, Ventures and Law Weekly, June 11th, 2006

Cardiology data are the focus of recent research from Canada, Sweden and the United States.

Study 1: Aprotinin and tranexamic acid have similar hemostatic effectiveness in high-transfusion-risk cardiac surgery.

According to a study from Canada, "Cardiac surgery with cardiopulmonary bypass may result in excessive fibrinolysis and platelet (PLT) dysfunction, resulting in impaired hemostasis and excessive blood loss. Prophylactic use of the antifibrinolytic drugs aprotinin and tranexamic acid is thought to prevent these hemostatic defects. Their relative clinical utility and safety in high-transfusion-risk cardiac surgery, however, is not known."

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