Published in Pharma Investments, Ventures and Law Weekly, July 9th, 2006
"Cyclooxygenase 2 (COX-2) overexpression is a frequent but not universal event in colorectal cancer. It has been suggested that COX-2 protein expression is reduced in colorectal cancer with a defective mismatch repair (MMR) system, a phenomenon commonly associated with hereditary nonpolyposis colorectal cancer but also present in up to 15% of sporadic tumors," scientists writing in the journal Clinical Cancer...
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