University of Helsinki, Finland
Women with select pregnancy complications display alterations of angiogenesis factors
Published in Pharma Investments, Ventures and Law Weekly, July 9th, 2006
According to a study from Finland, "Placental bed vascular function is compromised in pregnancies complicated by preeclampsia (PE), intrauterine growth retardation (IUGR), and maternal diabetes mellitus (DM). We performed an immunohistochemical analysis of vascular endothelial growth factor (VEGF), its receptors (VEGFR)-1 and -2, and the Tie-1 and -2 receptors in cryostat tissue sections of the placental bed from healthy women (n=5) and women with PE (n=5), IUGR (n=5), and DM (n=5)."
"VEGF immunoreactivity was stable between the study groups. VEGFR-1...
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