IRCCS, Italy
RD1 selected peptide assays have a higher diagnostic accuracy for active tuberculosis
Published in Pharma Investments, Ventures and Law Weekly, July 30th, 2006
"A previous case-control study reported that an in vitro interferon (IFN)-gamma response to early secreted antigenic target (ESAT)-6 selected peptides was associated with active tuberculosis (A-TB). The objective of the present pilot study was to evaluate the diagnostic accuracy of this assay for TB disease in a clinical setting," researchers in Italy report.
According to D. Goletti and colleagues at IRCCS in Rome, "An IFN-gamma ELISPOT assay was performed on samples from patients with suspected A-TB using two peptides selected from ESAT-6 protein and three...
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