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National Institute of Health, South Korea

In obesity induced by high-fat diets, low-dose genistein raised mitochondrial enzyme activities

Published in Pharma Investments, Ventures and Law Weekly, November 5th, 2006

In mouse model with fatty liver and obesity induced by high-fat diets, low-dose genistein increased mitochondrial enzyme activities.

"Genistein has been suggested to prevent insulin resistance and its related diseases. We investigated the effects of dietary genistein at different levels on hepatic lipid levels and mitochondrial functions in mice fed high-fat diets. C57BL/6J mice were randomly divided into four groups and fed a high-fat diet containing genistein at levels of 0, 0.1, 0.2, and 0.4% (HF, HF + 0.1G, HF + 0.2G, and HF + 0.4G) for 12 wk," investigators in South Korea report.

Y.M. Lee and colleagues working with the National Institute of...

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