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Cancer Gene Therapy

Scientists at University of Alabama, Gene Therapy Center release new data on cancer gene therapy

Published in Pharma Investments, Ventures and Law Weekly, November 19th, 2006

A new study, "Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma," is now available. According to a study from the United States, "Cholangiocarcinoma is a highly malignant neoplasm with no effective treatment. Conditionally replicative adenoviruses (CRAds) represent a promising new modality for the treatment of cancer in general."

"A key contribution in this regard was the introduction of tumor-selective viral replication for amplification of the initial inoculum in the neoplastic cell population. Under ideal conditions following cellular infection, the viruses replicate selectively in the infected tumor cells and kill the cells by...

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