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Isis and Alnylam win U.S. patent for chemical modifications of oligonucleotide therapeutics

Published in Pharma Investments, Ventures and Law Weekly, December 31st, 2006

Isis Pharmaceuticals, Inc., (ISIS) and Alnylam Pharmaceuticals, Inc., (ALNY) announced that a key patent was issued by the United States Patent & Trademark Office covering certain chemical modifications of oligonucleotides used to introduce "drug-like" properties in antisense oligonucleotides, including small interfering RNAs (siRNAs), the molecules that mediate RNA interference (RNAi).

The U.S. patent (U.S. patent no. 7,138,517) is owned by Isis and is licensed exclusively to Alnylam for double-stranded RNAi therapeutic applications pursuant to the terms of their 2004 collaboration and license agreement.

"Our intellectual property estate continues...

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