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Transplantation

Research from Innsbruck Medical University has provided new data on transplantation

Published in Pharma Investments, Ventures and Law Weekly, January 13th, 2008

According to recent research from Innsbruck, Austria, "Hereditary complete C4 deficiency (C4def) is a very rare condition that predisposes to immune complex disease and end-stage renal failure. Whether such patients should undergo renal transplantation is debated."

"The clinical outcome of five transplantations in three C4def patients is described. The first patient lost one allograft after 6 years because of chronic allograft rejection. Back on dialysis, he suffered from meningitis caused by Neisseria menigitidis and Aspergillus. One year after a second transplantation under alemtuzumab induction, he developed fulminant Kaposi's sarcoma and died. His sister is now 6...

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