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Enzyme Research

Investigators at National Institute of Standards and Technology have published new data on enzyme research

Published in Pharma Investments, Ventures and Law Weekly, January 13th, 2008

A new study, 'Association and redox properties of the putidaredoxin reductase-nicotinamide adenine dinucleotide complex,' is now available. "Putidaredoxin reductase (PdR) is the flavin protein that carries out the first electron transfer involved in the cytochrome P450cam catalytic cycle. In PdR, the flavin adenine dinucleotide (FAD/FADH2) redox center acts as a transformer by accepting two electrons from soluble nicotinamide adenine dinucleotide (NAD+/NADH) and donating them in two separate, one-electron-transfer steps to the iron-sulfur protein putidaredoxin (Pdx)," researchers in the United States report.

"PdR, like the two more intensively studied monoflavin...

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