Hypersensitivity

Findings in hypersensitivity reported from H. Faruki and co-researchers

Published in Pharma Investments, Ventures and Law Weekly, January 13th, 2008

According to recent research published in the journal Pharmacogenetics and Genomics, "HLA-B*5701 testing to provide risk stratification for abacavir hypersensitivity has the potential to reduce incidence of hypersensitivity reactions in susceptible individuals. Early experience with clinical HLA-B*5701 testing of the first 100 specimens, from a large clinical reference laboratory in the United States, is presented."

"Patient samples were tested using a two-step approach. The first step allowed rapid identification of most HLA-B*5701-negative samples in a high throughput mode. The second step involved resolution of putative positives by DNA sequencing to identify...

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Source: Pharma Investments, Ventures and Law Weekly (2008-01-13)

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