Multiple Sclerosis

Research reports from University of Basilicata provide new insights into multiple sclerosis

Published in Pharma Investments, Ventures and Law Weekly, January 20th, 2008

"We investigated whether polyunsaturated fatty acids (PUFA), which might be a useful complementary therapy among patients with multiple sclerosis (MS), are able to modulate matrix metalloproteinase (MMP) production in microglial cultures. MMPs are myelinotoxic factors," scientists in Potenza, Italy report.

"Primary cultures of rat microglia were treated with different doses of omega-3 (omega-3) PUFA or purified fish oil, containing a mixture of omega-3 and omega-6 PUFA, and simultaneously activated by exposure to lipopolysaccharide (LPS). Culture supernatants were subjected to zymography and Western blot analysis for the assessment of MMP-2 and MMP-9 levels. Increased...

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Source: Pharma Investments, Ventures and Law Weekly (2008-01-20)

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