Abdominal Aortic Aneurysm
Not Only Lipids and Inflammation: Insight Into a New Cause of Heart Attack and Other Vascular Disease
Published in Pharma Investments, Ventures and Law Weekly, January 20th, 2008
deCODE scientists report that the genetic variant on chromosome 9p21 that the company has linked to increased risk of heart attack is also associated with up to 70% increase in risk of abdominal aortic aneurysm (AAA) and intracranial aneurysm (IA). This is the first common genetic variant ever found to associate with either condition. The paper, entitled 'The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm,' is published in the online edition of Nature Genetics, at www.nature.com/ng.
AAA and IA are the most common aneurysms - balloon-like protrusions on arteries in the abdomen and head,...
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