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Acute Lymphocytic Leukemia Therapy
Researchers at Tokyo Medical and Dental University target acute lymphocytic leukemia therapy
March 2nd, 2008
Investigators publish new data in the report 'Successful high-dose methotrexate chemotherapy in a patient with acute lymphocytic leukemia who developed acute renal failure during the initial treatment.' According to a study from Tokyo, Japan, "Methotrexate (MTX) is a key drug in the chemotherapy for childhood acute lymphocytic leukemia (ALL). It is essential in the treatment of such areas as the central nervous system (CNS) and reproductive organs." "High-dose chemotherapy is applied for this purpose to obtain an effective plasma concentration in the target organs.There are three major mechanisms of nephrotoxicity related with MTX. One is that induced by allergic...
Source: Pharma Investments, Ventures & Law Weekly (2008-03-02)
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