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Pharma Investments, Ventures & Law Weekly

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Acidosis Therapy



Scientists at University of Medicine discuss research in acidosis therapy



March 9th, 2008

Researchers detail in 'Stewart's physicochemical approach in neurosurgical patients with hyperchloremic metabolic acidosis during propofol anesthesia,' new data in acidosis. According to a study from Korea, "There is both in vitro and clinical evidence that high-dose propofol can inhibit mitochondrial respiration, resulting in metabolic acidosis. The purpose of this study was to evaluate the effects of propofol anesthesia on the acid-base status in neurosurgical patients with large amount of normal saline administration."

"Thirty patients undergoing clipping of cerebral aneurysm were randomly assigned to receive propofol (n=15) or isoflurane (n=15). Propofol dose...


Source: Pharma Investments, Ventures & Law Weekly (2008-03-09)

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