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Adenovirus
New adenovirus study findings have been reported from Johns Hopkins University
March 9th, 2008
According to a study from the United States, "Capsid-displayed adenoviral peptide libraries have been a significant, yet unfeasible goal in biotechnology. Three barriers have made this difficult: the large size of the viral genome, the low efficiency of converting plasmid-based genomes into packaged adenovirus and the fact that library amplification is hampered by the ability of two (or more) virus to co-infect one cell." "Here, we present a novel vector system, pFex, which is capable of overcoming all three barriers. With pFex, modified fiber genes are recombined into the natural genetic locus of adenovirus through unidirectional Crelox recombination. Modified-fiber...
Source: Pharma Investments, Ventures & Law Weekly (2008-03-09)
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