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Pharma Investments, Ventures & Law Weekly

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Adenovirus



Recent findings from University of Iowa, Medical Department highlight research in adenovirus



March 9th, 2008

According to a study from the United States, "Adenoviral evolution has generated mechanisms to resist host cell defense systems, but the biochemical basis for evasion of multiple antiviral pathways in the airway by adenoviruses is incompletely understood. We hypothesized that adenoviruses modulate airway epithelial responses to type I interferons by altering the levels and activation of specific Janus family kinase-signal transducer and activator of transcription (JAK-STAT) signaling components."

"In this study, specific effects of adenovirus type 5 (AdV) on selected JAK-STAT signal transduction pathways were identified in human tracheobronchial epithelial cells, with...


Source: Pharma Investments, Ventures & Law Weekly (2008-03-09)

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