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Pharma Investments, Ventures & Law Weekly

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Adipose Tissue



Research from Q. Liu and co-researchers yields new findings on adipose tissue



March 9th, 2008

In this recent report published in the journal Acta Pharmacologica Sinica, researchers in Shanghai, People's Republic of China conducted a study "To characterize the in vitro bioactivities of rhodanine derivatives as novel peroxisome proliferator-activated receptor (PPAR) gamma modulators, based on a hit (SH00012671) identified during high-throughput screening (HTS) of a diverse synthetic compound library, and to preliminarily elucidate the structure-activity relationship of this class of PPAR gamma agonists. Full-length PPAR gamma and retinoid X receptor alpha (RXR alpha), biotinylated PPAR response element (PPRE), [H-3]BRL49653 (rosiglitazone), and streptavidin-coated FlashPlate...


Source: Pharma Investments, Ventures & Law Weekly (2008-03-09)

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