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Aging
Studies from University of Heidelberg, Department of Hematology-Oncology provide new data on aging
March 9th, 2008
A new study, 'Aging and anti-aging: unexpected side effects of everyday medication through sirtuin1 modulation,' is now available. "The sirtuin 1 protein (SIRT1) is a member of the class III NAD+-dependent histone deacetylases, which are also referred to as the 'sirtuins'. The sirtuins and silent information regulator 1 (SIRT1) in particular, are known to play a role in the response to DNA damage, metabolism, longevity and carcinogenesis," researchers in Heidelberg, Germany report. "SIRT1 regulates different cellular processes such as proliferation, differentiation and apoptosis through deacetylation of important regulatory proteins such as p53, FOXO3a and NFkappaB. A...
Source: Pharma Investments, Ventures & Law Weekly (2008-03-09)
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