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Pharma Investments, Ventures & Law Weekly

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Addiction Medicine



New research indicates that a common heart drug



March 16th, 2008

Researchers from Boston University School of Medicine and Harvard Medical School have found that diltiazem, a drug used in the treatment of high blood pressure, reduces cocaine cravings in a rat model. These findings will appear in the March issue of the leading medical journal Nature Neuroscience.

Previous work showed that two brain chemicals, dopamine and glutamate, independently contribute to the development of cocaine addiction. This new research indicates that calcium channels provide critical links between dopamine and glutamate that drives the intense craving associated with cocaine addiction. Diltiazem, one of a class of drugs known as calcium channel blockers,...


Source: Pharma Investments, Ventures & Law Weekly (2008-03-16)

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