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Acidosis
Research on acidosis discussed by C.C.G. Vanenckevort and co-researchers
March 23rd, 2008
"The plastic hardener methyl ethyl ketone peroxide (MEKP) is an unstable peroxide that releases free oxygen radicals. Ingestion of this compound induces widespread liver necrosis that is often fatal, extensive ulceration with subsequent scarring, and stenosis of the proximal digestive tract in survivors," investigators in The Hague, Netherlands report. "Severe metabolic acidosis occurs due to the accumulation of formic acid and other organic acids inducing neurologic damage, such as optic nerve lesions. A 53-year-old man unintentionally ingested approximately 120 ml of a 33% solution of this compound in dimethylphtalate. The patient was treated with the free radical...
Source: Pharma Investments, Ventures & Law Weekly (2008-03-23)
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