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Acute Lymphoblastic Leukemia
Researchers from University of Barcelona detail findings in acute lymphoblastic leukemia
March 23rd, 2008
According to a study from Barcelona, Spain, "CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells." "Monoclonal antibodies grouped in the CD66 cluster recognize CEACAM members. Ectopic CD66 expression is commonly detected in B-cell lineage acute lymphoblastic leukemia (ALL). To investigate the CEACAM messenger RNA (RNA) expression in leukemic blasts, we performed a quantitative polymerase chain reaction (RQ-PCR) analysis in purified...
Source: Pharma Investments, Ventures & Law Weekly (2008-03-23)
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