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Pharma Investments, Ventures & Law Weekly

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Acidosis



Researchers from University of Cordoba discuss findings in acidosis



March 30th, 2008

According to recent research from Cordoba, Spain, "Metabolic acidosis is common in patients with chronic kidney disease, which is known to affect bone metabolism. We examined the effect of metabolic acidosis on the development of vascular and other soft-tissue calcifications in uremic rats treated with calcitriol."

"Extraskeletal calcification was measured in vivo, in control rats and rats with a remnant kidney model of uremia with or without ammonium chloride-induced acidosis. Soft-tissue calcification was assessed histologically, by measurement of the expression of the sodium-dependent phosphate cotransporter Pit-1 and by quantification of tissue calcium and...


Source: Pharma Investments, Ventures & Law Weekly (2008-03-30)

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