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Pharma Investments, Ventures & Law Weekly

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Acne Vulgaris



New acne vulgaris research from Columbia University described



March 30th, 2008

"Higher free testosterone levels in women are a function of lower levels of sex hormone-binding globulins (SHBG), higher levels of total testosterone, or both. When free testosterone levels are decreased, sebum production, a pathogenic feature of acne vulgaris, is also decreased," investigators in the United States report.

"Oral contraceptives (OCs) decrease free testosterone levels by reducing testosterone production by the ovaries and adrenal glands, increasing SHBG, and inhibiting conversion of free testosterone to dihydrotestosterone. Studies have shown that the progestin component of OCs lowers androgen levels, which are directly associated with the development of...


Source: Pharma Investments, Ventures & Law Weekly (2008-03-30)

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