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Adenovirus
Scientists at Merck & Company, Inc. detail research in adenovirus
March 30th, 2008
"PER.C6 cells, an industrially relevant cell line for adenovirus manufacture, were extensively passaged in serum-free suspension cell culture to better adapt them to process conditions. The changes in cell physiology that occurred during this passaging were characterized by investigating cell growth, cell size, metabolism, and cultivation of replication-deficient adenovirus," researchers in the United States report. "The changes in cell physiology occurred gradually as the population doubling level, the number of times the cell population had doubled, increased. Higher passage PER.C6 (HP PER.C6) proliferated at a specific growth rate of 0.043 h(-1), 2-fold faster than...
Source: Pharma Investments, Ventures & Law Weekly (2008-03-30)
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