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Pharma Investments, Ventures & Law Weekly

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Adrenalectomy



Scientists at University of Sao Paulo, Department of Neurology discuss research in adrenalectomy



March 30th, 2008

Fresh data on adrenalectomy are presented in the report 'Adrenalectomy counteracts the local modulation of astroglial fibroblast growth factor system without interfering with the pattern of 6-OHDA-induced dopamine degeneration in regions of the ventral midbrain.' According to a study from Sao Paulo, Brazil, "The present study investigated the effects of bilateral adrenalectomy (ADX) on the synthesis of basic fibroblast growth factor (bFGF, FGF-2) mRNA and on the expression of its FGF receptor subtype-2 (FGFR2) mRNA after a 6-hydroxydopamine (6-OHDA)-induced lesion of nigrostriatal dopamine system. In previous papers we have demonstrated that corticosterone increases FGF-2 immunoreactivity...


Source: Pharma Investments, Ventures & Law Weekly (2008-03-30)

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