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Pharma Investments, Ventures & Law Weekly

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Adrenalectomy



Research from University of Padua provides new data on adrenalectomy



April 6th, 2008

"Cortisol secretion in ACTH-independent macronodular adrenal hyperplasia (AIMAH) may be regulated by the aberrant expression of several G-protein-coupled receptors. Bilateral adrenalectomy is the treatment of choice in most cases," investigators in Padua, Italy report.

"We searched for aberrant receptor expression in a patient with AIMAH and evaluated the response to medical and surgical treatment. A 35-year-old woman with amenorrhea, hirsutism, and hypertension presented ACTH-independent cortisol secretion with high androgen levels. Abdominal computed tomography showed bilateral adrenal macronodules (4.5 cm right and 1.0 cm left). Scintigraphy with I-131-norcholesterol...


Source: Pharma Investments, Ventures & Law Weekly (2008-04-06)

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