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Albuminuria
Research reports from University of Montreal provide new insights into albuminuria
April 6th, 2008
"The present study investigated the relationships between reactive oxygen species (ROS), interstitial fibrosis, and renal proximal tubular cell (RPTC) apoptosis in type 2 diabetic db/db mice and in db/db transgenic (Tg) mice overexpressing rat catalase (rCAT) in their RPTCs (db/db rCAT-Tg). Blood pressure, blood glucose, and albuminuria were monitored for up to 5 months," scientists writing in the journal Diabetes report. "Kidneys were processed for histology mid apoptosis studies (terminal transferase-mediated dUTP nick-end labeling or immunostaining for active caspase-3 and Bax). Real-time quantitative PCR assays were used to quantify angiotensinogen (ANG),...
Source: Pharma Investments, Ventures & Law Weekly (2008-04-06)
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