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Pharma Investments, Ventures & Law Weekly

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Algorithms



Researchers from University of Oslo, Institute of Basic Medical Science discuss findings in algorithms



April 6th, 2008

Data detailed in 'Accounting for haplotype phase uncertainty in linkage disequilibrium estimation' have been presented. "The characterization of linkage disequilibrium (LD) is applied in a variety of studies including the identification of molecular determinants of the local recombination rate, the migration and population history of populations, and the role of positive selection in adaptation. LD suffers from the phase uncertainty of the haplotypes used in its calculation, which reflects limitations of the algorithms used for haplotype estimation," investigators in Blindern, Norway report.

"We introduce a LD calculation method, which deals with phase uncertainty by...


Source: Pharma Investments, Ventures & Law Weekly (2008-04-06)

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