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Pharma Investments, Ventures & Law Weekly

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Acute Myelogenous Leukemia



Study findings on acute myelogenous leukemia are outlined in reports from C. Huisman and colleagues



April 13th, 2008

"Reduced intensity conditioning (RIC) protocols are increasingly used for allogeneic hematopoietic stem cell transplantation (HSCT) in elderly patients. We analyzed the outcome of RIC HSCT in acute myelogenous leukemia (AML) patients over the age of 40 years," scientists in Netherlands report.

"Forty-three AML or high-risk myelodysplastic syndrome (MDS) patients were treated with a fludarabine and low-dose total-body irradiation (TBI)-based pretransplantation regimen. Donors were HLA-compatible sibling (68%) or unrelated volunteers (34%). All but 2 AML patients were in complete remission (CR) at the time of transplantation. Seventy-six percent of patients had a poor...


Source: Pharma Investments, Ventures & Law Weekly (2008-04-13)

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