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Pharma Investments, Ventures & Law Weekly

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Alcoholism



Studies by O. Ameisen and co-authors describe new findings in alcoholism



April 13th, 2008

According to a study from Paris, France, "It has been hypothesized that the therapeutic effects of Gamma-hydroxybutyrate (GHB) in alcohol dependence could be related to ethanol-mimicking action of the drug and that GHB could reduce alcohol craving, intake and withdrawal by acting as a ''substitute'' of the alcohol in the central nervous system. Nevertheless, alcohol being the strongest trigger of craving and intake, it is difficult to ascribe reduction of craving and intake to ethanol-mimicking activity of GHB."

"I have recently proposed that alcohol/substance dependence could result from a GHB-deficiency-related dysphoric syndrome in which alcohol/substances would be...


Source: Pharma Investments, Ventures & Law Weekly (2008-04-13)

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