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Pharma Investments, Ventures & Law Weekly

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Alcoholism



Study results from University of Kansas provide new insights into alcoholism



April 13th, 2008

Fresh data on alcoholism are presented in the report 'The pathogenesis of ethanol versus methionine and choline deficient diet-induced liver injury.' "The differences and similarities of the pathogenesis of alcoholic (ASH) and non-alcoholic steatohepatitis (NASH) were examined. Mice (six/group) received one of four Lieber-Decarli liquid diets for 6 weeks: (1) paired-fed control diet; (2) control diet with ethanol (ethanol); (3) paired-fed methionine/choline deficient (MCD) diet; and (4) MCD plus ethanol (combination)," scientists in the United States report.

"Hepatotoxicity, histology, and gene expression changes were examined. Both MCD and ethanol induced...


Source: Pharma Investments, Ventures & Law Weekly (2008-04-13)

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