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Adenovirus
New findings in adenovirus described from University of Illinois, Department of Neurosurgery
April 20th, 2008
Current study results from the report, 'Downregulation of matrix metalloproteinase-2 (MMP-2) utilizing adenovirus-mediated transfer of small interfering RNA (siRNA) in a novel spinal metastatic melanoma model,' have been published. "Matrix metalloproteinases (MMPs) comprise a class of secreted zinc-dependent endopeptidases implicated in the metastatic potential of tumor cells due to their ability to degrade the extracellular matrix (ECM) and basement membrane. Matrix metalloproteinase-2 (MMP-2) has been detected in high levels and correlates with invasiveness in human melanoma," scientists in the United States report. "We have studied the effect of adenovirus-mediated...
Source: Pharma Investments, Ventures & Law Weekly (2008-04-20)
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