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Pharma Investments, Ventures & Law Weekly

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Abdominal Aortic Aneurysm



Reports outline abdominal aortic aneurysm study findings from T. Grzela and colleagues



April 20th, 2008

According to recent research from Warsaw, Poland, "Large abdominal aortic aneurysms (AAAs) are associated with coagulation abnormalities, which are significantly reduced by low molecular weight heparin (LMWH). Considering anti-inflammatory properties of heparin we verified, whether LMWH influences MMP-2/-9 in AAA patients."

"The study involved 26 AAA individuals, 10 patients with coagulation abnormalities received LMWH and 16 were a control group. The plasma activity of MMP-2/-9 was measured using zymography. We found that, in addition to the reduction of coagulation abnormalities, LMWH treatment was associated with the decreased MMP-9 but not MMP-2 activity," wrote T....


Source: Pharma Investments, Ventures & Law Weekly (2008-04-20)

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