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Pharma Investments, Ventures & Law Weekly

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Aging



Research results from University of Tennessee, Health Science Center update understanding of aging



April 20th, 2008

A report, 'Normal aging involves altered expression of growth factors in the rat choroid,' is newly published data in Journals of Gerontology Series a. According to recent research published in the Journals of Gerontology Series a, "Normal aging of the choroid results in morphological and physiological changes. The growth factors that mediate these changes are unclear."

"Vascular endothelial growth factor (VEGF) binds its receptor 2, VEGFR2, to mediate vascular remodeling. Pigment epithelium-derived factor (PEDF) is an inhibitor of angiogenesis produced by retinal pigmented epithelial (RPE) cells. Angiopoietin1 (Ang-1) binds its receptor Tie-2 to recruit...


Source: Pharma Investments, Ventures & Law Weekly (2008-04-20)

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