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Pharma Investments, Ventures & Law Weekly

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Acute Myeloid Leukemia



Scientists at Karolinska University discuss research in acute myeloid leukemia



April 27th, 2008

According to recent research from Huddinge, Sweden, "Chromosomal aberrations are important prognostic parameters in acute myeloid leukemia (AML). Indicators of poor prognosis include del(5q)/-5, del(7q)/-7, abnormal 3q or complex karyotype."

"In recent years, it has become clear that aberrations in 17p represent one of the indicators of poor prognosis in haematological malignancies. In AML, deletions in 17p have been shown to indicate a dismal prognosis; genetic aberrations in 9p have also been discussed as influencing long-term survival in AML. In this study, we correlated genetic abnormalities in chromosomes 9 and 17 in patients with de novo AML to in vitro...


Source: Pharma Investments, Ventures & Law Weekly (2008-04-27)

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