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Acute Myeloid Leukemia Cell Biology
Investigators at Northwestern University release new data on acute myeloid leukemia cell biology
April 27th, 2008
A report, 'Constitutive activation of SHP2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia,' is newly published data in The Journal of Clinical Investigation. According to recent research from the United States, "Myeloproliferative disorders (MPDs) are characterized by cytokine hypersensitivity and apoptosis resistance. Development of a block in myeloid differentiation is associated with progression of MPD to acute myeloid leukemia (AML) and portends poor prognosis." "Identifying molecular markers of this transition may suggest targets for therapeutic intervention. Interferon consensus sequence binding protein (ICSBP,...
Source: Pharma Investments, Ventures & Law Weekly (2008-04-27)
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